Dnmt3b Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:346060 Huang X, et al., ZFP281 controls transcriptional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1. Dev Cell. 2024 Feb 26;59(4):465-481.e6
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7643611
Gene symbol:	Dnmt3b
Gene name:	DNA methyltransferase 3B

Antibody:	anti-Dnmt3b
Detection system:	Secondary antibody

Results

Specimen 2B WT: embryonic day 6.5 (more

)
Note: Triple labeled: green - Dnmt3b; red - Sox2 (assay MGI:7643614); blue - Hoechst.

Structure	Level	Pattern	Image	Note
TS8: epiblast	Present		2B WT DNMT3B , 2B WT Merge

Specimen 2B Zfp281-/-: embryonic day 6.5; Zfp281^tm1.1Jlwa/Zfp281^tm1.1Jlwa (more

)
Note: Triple labeled: green - Dnmt3b; red - Sox2 (assay MGI:7643614); blue - Hoechst.

Structure	Level	Pattern	Image	Note
TS8: epiblast	Present		2B Zfp281-/- DNMT3B , 2B Zfp281-/- Merge	Expression levels are significantly reduced in the mutant relative to wild type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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