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Gene Expression Data
Assay Details
Assay
Reference: J:195264 Vincentz JW, et al., Twist1 Controls a Cell-Specification Switch Governing Cell Fate Decisions within the Cardiac Neural Crest. PLoS Genet. 2013 Mar;9(3):e1003405
Assay type: RNA in situ
MGI Accession ID: MGI:7643405
Gene symbol: Twist1
Gene name: twist basic helix-loop-helix transcription factor 1
Probe: Twist1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen S1A: embryonic day 10.5 (more )
Structure Cell Type Level Pattern Image Note
TS17: outflow tract endocardial cushion neural crest cell Present S1A
TS17: endocardial lining Present S1A
Specimen S1B: embryonic day 10.5; H2az2Tg(Wnt1-cre)11Rth/0, Twist1tm1Bhr/Twist1tm2Bhr (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS17: outflow tract endocardial cushion neural crest cell Absent S1B Expression was lost in cardiac neural crest cells in the aorticopulmonary cushion mesenchyme.
TS17: endocardial lining Present S1B Endocardium staining was not affected in the conditional mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory