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Gene Expression Data
Assay Details
Assay
Reference: J:290791 Baba Y, et al., Sall1 plays pivotal roles for lens fiber cell differentiation in mouse. Biochem Biophys Res Commun. 2019 May 14;512(4):927-933
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7641977
Gene symbol: Sall1
Gene name: spalt like transcription factor 1
Reporter: GFP
Antibody: anti-GFP (abcam)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1B E11.5: embryonic day 11.5; Sall1tm3Ryn/Sall1+ (more )
Structure Level Pattern Image Note
TS19: lens vesicle Weak 1B E11.5
TS19: retina Present 1B E11.5
Specimen 1B E12.5: embryonic day 12.5; Sall1tm3Ryn/Sall1+ (more )
Structure Level Pattern Image Note
TS20: lens vesicle Present Widespread 1B E12.5
TS20: retina Weak 1B E12.5
Specimen 1B E13.5: embryonic day 13.5; Sall1tm3Ryn/Sall1+ (more )
Structure Level Pattern Image Note
TS21: lens Strong Regionally restricted 1B E13.5 Strong signals were observed in the posterior region of the lens where the lens nucleus was localized, and weak expression was observed in the lens epithelium.
TS21: lens epithelium Weak 1B E13.5
TS21: lens fiber Strong 1B E13.5
TS21: retina Weak 1B E13.5
Specimen 1B E14.5: embryonic day 14.5; Sall1tm3Ryn/Sall1+ (more )
Structure Level Pattern Image Note
TS22: lens fiber Strong 1B E14.5
TS22: lens epithelium Weak 1B E14.5
TS22: retina Trace 1B E14.5 Expression mostly disappeared.
Specimen 1B E15.5: embryonic day 15.5; Sall1tm3Ryn/Sall1+ (more )
Structure Level Pattern Image Note
TS23: lens fiber Strong 1B E15.5
TS23: lens epithelium Present 1B E15.5 Increased expression.
Specimen 1C P1: postnatal day 1; Sall1tm3Ryn/Sall1+ (more )
Structure Level Pattern Image Note
TS27: lens epithelium Present 1C P1
TS27: lens fiber Present 1C P1
Specimen 1C P5: postnatal day 5; Sall1tm3Ryn/Sall1+ (more )
Structure Level Pattern Image Note
TS28: lens epithelium Strong 1C P5
TS28: lens fiber Present 1C P5
Specimen 1C P12: postnatal day 12; Sall1tm3Ryn/Sall1+ (more )
Structure Level Pattern Image Note
TS28: lens epithelium Strong 1C P12
TS28: lens fiber Present 1C P12
Specimen 1C adult: postnatal adult; Sall1tm3Ryn/Sall1+ (more )
Structure Level Pattern Image Note
TS28: lens epithelium Strong 1C adult
TS28: lens fiber Present 1C adult
Specimen 1D Pax6/EGFP: postnatal day 12; Sall1tm3Ryn/Sall1+ (more )
Note: Double labeled: green - Sall1 reporter; red - Pax6 (assay MGI:7641980).
Structure Level Pattern Image Note
TS28: lens epithelium Present 1D-1 , 1D-3 Coexpressed with Pax6.
TS28: lens fiber Present 1D-1 , 1D-3 Coexpressed with Pax6.
Specimen 1D Prox1/EGFP: postnatal day 12; Sall1tm3Ryn/Sall1+ (more )
Note: Double labeled: green - Sall1 reporter; red - Prox1 (assay MGI:7641981).
Structure Level Pattern Image Note
TS28: lens epithelium Present 1D-6 , 1D-4 Coexpressed with Prox1.
TS28: lens fiber Present 1D-6 , 1D-4 Coexpressed with Prox1.
Specimen 2 E11.5: embryonic day 11.5; Sall1tm3Ryn/Sall1tm3Ryn (more )
Structure Level Pattern Image Note
TS19: lens vesicle Present 2-4
TS19: retina Present 2-4
Specimen 2 E12.5: embryonic day 12.5; Sall1tm3Ryn/Sall1tm3Ryn (more )
Structure Level Pattern Image Note
TS20: lens vesicle Present 2-5
TS20: retina Weak 2-5
Specimen 2 E13.5: embryonic day 13.5; Sall1tm3Ryn/Sall1tm3Ryn (more )
Structure Level Pattern Image Note
TS21: lens Present 2-6 There were several abnormal vacuole-like structures in the central region.
Specimen 2 E14.5: embryonic day 14.5; Sall1tm3Ryn/Sall1tm3Ryn (more )
Structure Level Pattern Image Note
TS22: lens Present 2-10 There was no adherence between the lens epithelium and apical ends of the lens fibers, and there was a gap under the lens epithelium.
Specimen 2 E15.5: embryonic day 15.5; Sall1tm3Ryn/Sall1tm3Ryn (more )
Structure Level Pattern Image Note
TS23: lens Present 2-11 The vacuoles were apparent, and the center of the lens had a mesh-like structure because of the large number of vacuoles.
Specimen 2 E16.5: embryonic day 16.5; Sall1tm3Ryn/Sall1tm3Ryn (more )
Structure Level Pattern Image Note
TS24: lens Present 2-12
Specimen S1C gfp/w: embryonic day 14.5; Sall1tm3Ryn/Sall1+ (more )
Structure Level Pattern Image Note
TS22: lens fiber Present S1C lower middle
TS22: lens epithelium Weak S1C lower middle
Specimen S1C gfp/gfp: embryonic day 14.5; Sall1tm3Ryn/Sall1tm3Ryn (more )
Structure Level Pattern Image Note
TS22: lens fiber Strong S1C lower right
TS22: lens epithelium Present S1C lower right
Specimen S2 gfp/w: postnatal; Sall1tm3Ryn/Sall1+ (more )
Note: Double labeled: green - Sall1 reporter; red - Ptprc (assay MGI:7641984).
Structure Cell Type Level Pattern Image Note
TS28: retina ganglion cell layer microglial cell Present S2_middle upper , S2_middle lower , S2_right lower merge , S2_right lower GFP , S2_right upper Coexpressed with CD45.2/Ptprc.
TS28: retina ganglion cell layer astrocyte Present S2_middle upper , S2_right lower GFP , S2_right upper , S2_right lower merge , S2_middle lower Not coexpressed with CD45.2/Ptprc.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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