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Gene Expression Data
Assay Details
Assay
Reference: J:160964 Li J, et al., Myocardin-related transcription factor B is required in cardiac neural crest for smooth muscle differentiation and cardiovascular development. Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):8916-21
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7628743
Gene symbol: Mrtfb
Gene name: myocardin related transcription factor B
Reporter: lacZ
Direct Detection
Results
Specimen 3A: embryonic day 8.5; MrtfbGt(RRJ478)Byg/Mrtfb+ (more )
Structure Level Pattern Image Note
TS13: rhombomere 3 Strong 3A
TS13: rhombomere 5 Strong 3A
TS13: heart Strong Widespread 3A
Specimen 3C: embryonic day 9.5; MrtfbGt(RRJ478)Byg/Mrtfb+ (more )
Structure Level Pattern Image Note
TS15: heart Strong Widespread 3C
TS15: branchial arch artery Present 3C
TS15: dorsal aorta Present 3C
TS15: outflow tract Present 3C
Specimen 3D/E: embryonic day 11.5; MrtfbGt(RRJ478)Byg/Mrtfb+ (more )
Structure Level Pattern Image Note
TS19: 3rd arch artery Present Regionally restricted 3E , 3D Expressed in the cells populating the mesenchyme surrounding aortic arch artery.
TS19: 4th arch artery Present Regionally restricted 3D Expressed in the cells populating the mesenchyme surrounding aortic arch artery.
TS19: 6th arch artery Present Regionally restricted 3D Expressed in the cells populating the mesenchyme surrounding aortic arch artery.
Specimen 3E inset: embryonic day 11.5; MrtfbGt(RRJ478)Byg/Mrtfb+ (more )
Note: Double labeled: blue - Mrtfb reporter; orange - Acta2 (assay MGI:7628744).
Structure Level Pattern Image Note
TS19: 3rd arch artery Present Regionally restricted 3E inset Coexpressed with Acta2 in the cells populating the mesenchyme surrounding aortic arch artery.
Specimen 5B: embryonic day 11.5; MrtfbGt(RRJ478)Byg/MrtfbGt(RRJ478)Byg (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: branchial arch Present 5B
TS19: mandible primordium Present 5B
TS19: outflow tract Present 5B
Specimen 5C: embryonic day 11.5; MrtfbGt(RRJ478)Byg/MrtfbGt(RRJ478)Byg (more )
Structure Level Pattern Image Note
TS19: branchial arch Absent 5C
TS19: mandible primordium Absent 5C
TS19: outflow tract Absent 5C
TS19: embryo Present Regionally restricted 5C Expression was virtually identical, except in the neural crest-derived regions of mandible, pharyngeal arches, and cardiac outflow tract.
Specimen not shown: embryonic day 10.5; MrtfbGt(RRJ478)Byg/Mrtfb+ (more )
Structure Level Pattern Image Note
TS17: branchial arch artery Present
TS17: dorsal aorta Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory