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Gene Expression Data
Assay Details
Assay
Reference: J:340774 Rothe B, et al., Bicc1 ribonucleoprotein complexes specifying organ laterality are licensed by ANKS6-induced structural remodeling of associated ANKS3. PLoS Biol. 2023 Sep;21(9):e3002302
Assay type: RNA in situ
MGI Accession ID: MGI:7628181
Gene symbol: Nodal
Gene name: nodal growth differentiation factor
Probe: Nodal probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1B 4-somite control: embryonic day 8.0 (more )
Note: 4-somite stage embryo
Structure Level Pattern Image Note
TS12: node Present Regionally restricted 1B 4-somite control Expression specifically on left side.
TS12: lateral plate mesoderm Present Regionally restricted 1B 4-somite control Expression specifically on left side.
Specimen 1B 4-somite delta/delta (left): embryonic day 8.0; Anks3em1Dbc/Anks3em1Dbc (more )
Note: 4-somite stage embryo
Structure Level Pattern Image Note
TS12: node Present Regionally restricted 1B 4-somite delta/delta (left) Expression bilaterally symmetric at node.
TS12: lateral plate mesoderm Absent 1B 4-somite delta/delta (left) Expression lost in lateral plate mesoderm in 3 out of 4 mutant embryos.
Specimen 1B 4-somite delta/delta (right): embryonic day 8.0; Anks3em1Dbc/Anks3em1Dbc (more )
Note: 4-somite stage embryo
Structure Level Pattern Image Note
TS12: node Present Regionally restricted 1B 4-somite delta/delta (right) Expression bilaterally symmetric at node.
TS12: lateral plate mesoderm Present Regionally restricted 1B 4-somite delta/delta (right) Expression bilateral in lateral plate mesoderm in 1 out of 4 mutant embryos.
Specimen 1B 7-comite control: embryonic day 8.0 (more )
Note: 7-somite stage embryo
Structure Level Pattern Image Note
TS12: node Present Regionally restricted 1B 7-somite control Expression specifically on left side.
TS12: lateral plate mesoderm Absent 1B 7-somite control Expression on left side of lateral plate mesoderm ceases before 7-somite stage.
Specimen 1B 7-comite delta/delta (left): embryonic day 8.0; Anks3em1Dbc/Anks3em1Dbc (more )
Note: 7-somite stage embryo
Structure Level Pattern Image Note
TS12: node Present Regionally restricted 1B 7-somite delta/delta (left) Expression bilaterally symmetric at node.
TS12: lateral plate mesoderm Present Regionally restricted 1B 7-somite delta/delta (left) Significant expression perisists in lateral plate mesoderm on left side in 1 out of of 2 embryos.
Specimen 1B 7-comite delta/delta (right): embryonic day 8.0; Anks3em1Dbc/Anks3em1Dbc (more )
Note: 7-somite stage embryo
Structure Level Pattern Image Note
TS12: node Present Regionally restricted 1B 7-somite delta/delta (right) Expression bilaterally symmetric at node.
TS12: lateral plate mesoderm Absent 1B 7-somite delta/delta (right) Expression lost in lateral plate mesoderm in 1 out of 2 embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory