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Gene Expression Data
Assay Details
Assay
Reference: J:249375 Smiley S, et al., Establishment of a cone photoreceptor transplantation platform based on a novel cone-GFP reporter mouse line. Sci Rep. 2016 Mar 11;6:22867
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7624343
Gene symbol: Opn1sw
Gene name: opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
Antibody: Anti-Blue opsin (AB5407)
Detection system: Secondary antibody
Results
Specimen 1c: postnatal adult; Ccdc136Gt(373F8)Cmhd/Ccdc136Gt(373F8)Cmhd (more )
Note: Double labeled: red - Opn1sw; green - Ccdc136 reporter (assay MGI:7624337).
Structure Level Pattern Image Note
TS28: retina outer nuclear layer Present Graded 1c right A ventral-to-dorsal gradient (high to low) was seen.
Specimen 2 dorsal WT: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: photoreceptor layer outer segment S cone cell Weak 2_6-2 , 2_6-1 Low to undetectable in the dorsal retina.
Specimen 2 dorsal GFP/GFP: postnatal adult; Ccdc136Gt(373F8)Cmhd/Ccdc136Gt(373F8)Cmhd (more )
Note: Double labeled: red - Opn1sw; green - Ccdc136 reporter (assay MGI:7624337).
Structure Cell Type Level Pattern Image Note
TS28: photoreceptor layer outer segment S cone cell Weak 2_6-5 , 2_6-3 Low to undetectable in the dorsal retina.
Specimen 2 ventral WT: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: photoreceptor layer outer segment S cone cell Present 2_7-2 , 2_7-1
Specimen 2 ventral GFP/GFP: postnatal adult; Ccdc136Gt(373F8)Cmhd/Ccdc136Gt(373F8)Cmhd (more )
Note: Double labeled: red - Opn1sw; green - Ccdc136 reporter (assay MGI:7624337).
Structure Cell Type Level Pattern Image Note
TS28: photoreceptor layer outer segment S cone cell Present 2_7-5 , 2_7-3 Expression overlapped with GFP-expressing cells in the ventral retina.
Specimen S4a: postnatal adult; Ccdc136Gt(373F8)Cmhd/Ccdc136Gt(373F8)Cmhd, Nrltm1Asw/Nrltm1Asw (more )
Note: Double labeled: red - Opn1sw; green - Ccdc136 reporter (assay MGI:7624337).
Structure Cell Type Level Pattern Image Note
TS28: photoreceptor layer outer segment S cone cell Present S4a merge-4 , S4a S opsin A shortened outer segment was shown, similar as in Nrl-/-.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory