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Gene Expression Data
Assay Details
Assay
Reference: J:264015 Roy AR, et al., The transcriptional regulator CCCTC-binding factor limits oxidative stress in endothelial cells. J Biol Chem. 2018 Jun 1;293(22):8449-8461
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7624262
Gene symbol: Ctcf
Gene name: CCCTC-binding factor
Results
Specimen 1A E9.5: embryonic day 9.5 (more )
Note: Double labeled: red - Ctcf; green - Pecam1 (assay MGI:7624263).
Structure Cell Type Level Pattern Image Note
TS15: 3rd branchial arch blood vessel endothelial cell Present Ubiquitous 1A E9.5 (merged) , 1A E9.5 Ctcf Ubiquitous expression in vascular endothelial cell nuclei.
Specimen 1A E11.5: embryonic day 11.5 (more )
Note: Double labeled: red - Ctcf; green - Pecam1 (assay MGI:7624263).
Structure Cell Type Level Pattern Image Note
TS19: outflow tract endothelium cardiac endothelial cell Present Ubiquitous 1A E11.5 (merged) , 1A E11.5 Ctcf Ubiquitous expression in vascular endothelial cell nuclei.
Specimen 1A P2: postnatal day 2 (more )
Note: Double labeled: red - Ctcf; green - Pecam1 (assay MGI:7624263).
Structure Cell Type Level Pattern Image Note
TS27: aorta aortic endothelial cell Present Ubiquitous 1A P2 (merged) , 1A P2 Ctcf Ubiquitous expression in vascular endothelial cell nuclei.
Specimen 1A 6 wks: postnatal week 6 (more )
Note: Double labeled: red - Ctcf; green - Pecam1 (assay MGI:7624263).
Structure Cell Type Level Pattern Image Note
TS28: pulmonary artery pulmonary artery endothelial cell Present Ubiquitous 1A 6 wks (merged) , 1A 6 wks Ctcf Ubiquitous expression in vascular endothelial cell nuclei.
Specimen S1A Ctcf fl/fl: embryonic day 10.5; Ctcftm2Gal/Ctcftm2Gal (more )
Note: Double labeled: red - Ctcf; green - Pecam1 (assay MGI:7624263).
Structure Cell Type Level Pattern Image Note
TS17: outflow tract endothelium cardiac endothelial cell Present S1A Ctcf fl/fl (lower)
Specimen S1A Ctcf fl/fl/ Tie2-cre: embryonic day 10.5; Ctcftm2Gal/Ctcftm2Gal, Tg(Tek-cre)#Rwng/0 (more )
Note: Conditional mutant. Double labeled: red - Ctcf; green - Pecam1 (assay MGI:7624263).
Structure Cell Type Level Pattern Image Note
TS17: outflow tract endothelium cardiac endothelial cell Trace S1A Tie2-cre (lower) Authors report over 90% fewer cell nuclei co-expressing Pecam1 compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory