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Gene Expression Data
Assay Details
Assay
Reference: J:264015 Roy AR, et al., The transcriptional regulator CCCTC-binding factor limits oxidative stress in endothelial cells. J Biol Chem. 2018 Jun 1;293(22):8449-8461
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7624263
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: MEC 13.3
Results
Specimen 1A E9.5: embryonic day 9.5 (more )
Note: Double labeled: green - Pecam1; red - Ctcf (assay MGI:7624262).
Structure Cell Type Level Pattern Image Note
TS15: 3rd branchial arch blood vessel endothelial cell Present 1A E9.5 Pecam-1 , 1A E9.5 (merged)
Specimen 1A E11.5: embryonic day 11.5 (more )
Note: Double labeled: green - Pecam1; red - Ctcf (assay MGI:7624262).
Structure Cell Type Level Pattern Image Note
TS19: outflow tract endothelium cardiac endothelial cell Present 1A E11.5 Pecam-1 , 1A E11.5 (merged)
Specimen 1A P2: postnatal day 2 (more )
Note: Double labeled: green - Pecam1; red - Ctcf (assay MGI:7624262).
Structure Cell Type Level Pattern Image Note
TS27: aorta aortic endothelial cell Present 1A P2 Pecam-1 , 1A P2 (merged)
Specimen 1A 6 wks: postnatal week 6 (more )
Note: Double labeled: green - Pecam1; red - Ctcf (assay MGI:7624262).
Structure Cell Type Level Pattern Image Note
TS28: pulmonary artery pulmonary artery endothelial cell Present 1A 6 wks Pecam-1 , 1A 6 wks (merged)
Specimen S1A Ctcf fl/fl: embryonic day 10.5; Ctcftm2Gal/Ctcftm2Gal (more )
Note: Double labeled: green - Pecam1; red - Ctcf (assay MGI:7624262).
Structure Cell Type Level Pattern Image Note
TS17: outflow tract endothelium cardiac endothelial cell Present S1A Ctcf fl/fl (upper) , S1A Ctcf fl/fl (lower)
Specimen S1A Ctcf fl/fl; Tie2-cre: embryonic day 10.5; Ctcftm2Gal/Ctcftm2Gal, Tg(Tek-cre)#Rwng/0 (more )
Note: Conditional mutant. Double labeled: green - Pecam1; red - Ctcf (assay MGI:7624262).
Structure Cell Type Level Pattern Image Note
TS17: outflow tract endothelium cardiac endothelial cell Present S1A Tie2-Cre (upper) , S1A Tie2-cre (lower)
Specimen 2B E8.5 Ctcf fl/fl: embryonic day 8.5; Ctcftm2Gal/Ctcftm2Gal (more )
Structure Level Pattern Image Note
TS13: yolk sac blood vessel Present 2B E8.5 Pecam-1 Ctcf fl/fl
Specimen 2B E8.5 Ctcf fl/fl; Tie2-cre: embryonic day 8.5; Ctcftm2Gal/Ctcftm2Gal, Tg(Tek-cre)#Rwng/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS13: yolk sac blood vessel Present 2B E8.5 Pecam-1 Tie2-Cre Blood vessel area, vessel length and lacunarity comparable to control.
Specimen 2B E9.5 Ctcf fl/fl: embryonic day 9.5; Ctcftm2Gal/Ctcftm2Gal (more )
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present 2B E9.5 Pecam-1 Ctcf fl/fl
Specimen 2B E9.5 Ctcf fl/fl; Tie2-cre: embryonic day 9.5; Ctcftm2Gal/Ctcftm2Gal, Tg(Tek-cre)#Rwng/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present 2B E9.5 Pecam-1 Tie2-Cre Blood vessel area and length decreased, and lacunarity increased, compared to control.
Specimen 2B E10.5 Ctcf fl/fl: embryonic day 10.5; Ctcftm2Gal/Ctcftm2Gal (more )
Structure Level Pattern Image Note
TS17: yolk sac blood vessel Present 2B E10.5 Pecam-1 Ctcf fl/fl
Specimen 2B E10.5 Ctcf fl/fl; Tie2-cre: embryonic day 10.5; Ctcftm2Gal/Ctcftm2Gal, Tg(Tek-cre)#Rwng/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: yolk sac blood vessel Present 2B E10.5 Pecam-1 Tie2-Cre Blood vessel area and length decreased, and lacunarity increased, compared to control.
Specimen S2A Ctcf fl/+; Tie2-cre: embryonic day 9.5; Ctcftm2Gal/Ctcf+, Tg(Tek-cre)#Rwng/0 (more )
Note: Conditional mutant. Double labeled: green - Pecam1; red - Casp3 (assay MGI:7624265).
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present S2A Ctcf fl/+; Tie2-Cre
Specimen S2A Ctcf fl/fl; Tie2-cre: embryonic day 9.5; Ctcftm2Gal/Ctcftm2Gal, Tg(Tek-cre)#Rwng/0 (more )
Note: Conditional mutant. Double labeled: green - Pecam1; red - Casp3 (assay MGI:7624265).
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present S2A Ctcf fl/fl; Tie2-Cre
Specimen S2B Ctcf fl/+; Tie2-cre: embryonic day 9.5; Ctcftm2Gal/Ctcf+, Tg(Tek-cre)#Rwng/0 (more )
Note: Conditional mutant. Double labeled: green - Pecam1; red - phospho-histone H3..
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present S2B Ctcf fl/+; Tie2-Cre
Specimen S2B Ctcf fl/fl; Tie2-cre: embryonic day 9.5; Ctcftm2Gal/Ctcftm2Gal, Tg(Tek-cre)#Rwng/0 (more )
Note: Conditional mutant. Double labeled: green - Pecam1; red - phospho-histone H3..
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present S2B Ctcf fl/fl; Tie2-Cre
Specimen 6I Ctcf fl/+; Tie2-Cre; Rosa mT/mG/+: embryonic day 9.5; Ctcftm2Gal/Ctcf+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Tek-cre)#Rwng/0 (more )
Note: Conditional mutant. Double labeled: green - Pecam1; red - Iscu (assay MGI:7624266).
Structure Level Pattern Image Note
TS15: labyrinthine zone Present 6I Ctcf fl/+ (lower) , 6I Ctcf fl/+ (upper)
Specimen 6I Ctcf fl/fl; Tie2-Cre; Rosa mT/mG/+: embryonic day 9.5; Ctcftm2Gal/Ctcftm2Gal, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Tek-cre)#Rwng/0 (more )
Note: Conditional mutant. Double labeled: green - Pecam1; red - Iscu (assay MGI:7624266).
Structure Level Pattern Image Note
TS15: labyrinthine zone Present 6I Ctcf fl/fl (upper) , 6I Ctcf fl/fl (lower)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
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