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Gene Expression Data
Assay Details
Assay
Reference: J:314103 Ulmke PA, et al., Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex. Stem Cell Reports. 2021 Apr 13;16(4):968-984
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7621644
Gene symbol: Rbfox3
Gene name: RNA binding protein, fox-1 homolog (C. elegans) 3
Antibody: anti-NeuN
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S6C Control: embryonic day 12.5 (more )
Note: Double labeled: green - Rbfox3; red - Casp3 (assay MGI:7621641).
Structure Cell Type Level Pattern Image Note
TS20: cerebral cortex cerebral cortex neuron Present Regionally restricted S6C Control low mag , S6C Control high mag Expression was detected in postmitotic neurons.
Specimen S6C EXCO2cKO: embryonic day 12.5; Emx1tm1(cre)Krj/Emx1+, Esco2tm1.1Ge/Esco2tm1.1Ge (more )
Note: Conditional mutant. Double labeled: green - Rbfox3; red - Casp3 (assay MGI:7621641).
Structure Cell Type Level Pattern Image Note
TS20: cerebral cortex cerebral cortex neuron Present Regionally restricted S6C ESCO2cKO low mag , S6C ESCO2cKO high mag Expression was detected in postmitotic neurons. Increased apoptotis (Casp3+) was noted in the conditional mutant, particularly in the dorsal cortical area.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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