Rr473em2Mbu
Endonuclease-mediated Allele Detail
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| Symbol: |
Rr473em2Mbu |
| Name: |
regulatory region 473; endonuclease-mediated mutation 2, Meinrad Busslinger |
| MGI ID: |
MGI:7620305 |
| Synonyms: |
WapldeltaP1,P2 |
| Gene: |
Rr473 Location: unknown Genetic Position: Chr14, Syntenic
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| Alliance: |
Rr473em2Mbu page
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| Allele Type: |
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Endonuclease-mediated (Modified regulatory region) |
| Mutation: |
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Intragenic deletion
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Mutation details: CRISPR-targeting deleted 10 bp from the 5' Pax5 binding site (P1) along with the nucleotide substitutions CCT to TGC and 5 bp subsequent to the P1 site.
(J:294166)
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| Inheritance: |
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Not Specified |
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Rr473 Mutation: |
0 strains or lines available
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This allele was generated in conjunction with Rr474em2Mbo. |
| Original: |
J:294166 Hill L, et al., Wapl repression by Pax5 promotes V gene recombination by Igh loop extrusion. Nature. 2020 Aug;584(7819):142-147 |
| All: |
1 reference(s) |
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Analysis Tools
