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Gene Expression Data
Assay Details
Assay
Reference: J:314655 Cesca F, et al., Kidins220/ARMS is an essential modulator of cardiovascular and nervous system development. Cell Death Dis. 2011 Nov 3;2:e226
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7619000
Gene symbol: Casp3
Gene name: caspase 3
Results
Specimen 7Da: embryonic day 16.5; Kidins220tm1.1Fces/Kidins220tm1.1Fces, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: neocortex Present Regionally restricted 7Da An increase in apoptosis was observed in the cingulate cortex compared with wild type.
Specimen 7Db: embryonic day 16.5; Kidins220tm1.1Fces/Kidins220tm1.1Fces (more )
Structure Level Pattern Image Note
TS24: neocortex Ambiguous 7Db
Specimen 7Dc: embryonic day 16.5; Kidins220tm1.1Fces/Kidins220tm1.1Fces, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: ventral posterior lateral thalamic nucleus Present 7Dc Increased apoptosis was observed in the mutant compared with wild type.
TS24: ventral posterior medial thalamic nucleus Present 7Dc Increased apoptosis was observed in the mutant compared with wild type.
TS24: midline thalamic group Absent 7Dc No apparent cell death was observed in the reuniens nucleus surrounding the third ventricle.
Specimen 7Dd: embryonic day 16.5; Kidins220tm1.1Fces/Kidins220tm1.1Fces (more )
Structure Level Pattern Image Note
TS24: ventral posterior lateral thalamic nucleus Ambiguous 7Dd
TS24: ventral posterior medial thalamic nucleus Ambiguous 7Dd
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/24/2026
MGI 6.24 		The Jackson Laboratory