Casp3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:314655 Cesca F, et al., Kidins220/ARMS is an essential modulator of cardiovascular and nervous system development. Cell Death Dis. 2011 Nov 3;2:e226
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7618840
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:	anti-activated Caspase 3 (AF835)
Detection system:	Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase

Results

4Aa ©

Specimen 4Aa: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: vestibular ganglion	Present		4Aa

4Ab ©

Specimen 4Ab: embryonic day 14.5; Kidins220^tm1.2Fces/Kidins220^tm1.2Fces (more

)

Structure	Level	Pattern	Image	Note
TS22: vestibular ganglion	Present		4Ab	Increased apoptosis was observed in the mutant vestibular ganglion.

4Ac ©

Specimen 4Ac: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: glossopharyngeal ganglion	Present		4Ac

4Ad ©

Specimen 4Ad: embryonic day 14.5; Kidins220^tm1.2Fces/Kidins220^tm1.2Fces (more

)

Structure	Level	Pattern	Image	Note
TS22: glossopharyngeal ganglion	Present		4Ad	Increased apoptosis was observed in the mutant glossopharyngeal ganglion.

4Ae ©

Specimen 4Ae: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: trigeminal ganglion	Present		4Ae

4Af ©

Specimen 4Af: embryonic day 14.5; Kidins220^tm1.2Fces/Kidins220^tm1.2Fces (more

)

Structure	Level	Pattern	Image	Note
TS22: trigeminal ganglion	Present		4Af	Apoptosis was observed in the mutant trigeminal ganglion, but the difference from wild type was not statistically significant.

5+/+ ©

Specimen 5 +/+: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: brain	Absent		5+/+
TS21: forebrain	Absent		5+/+

5-/- ©

Specimen 5 Kidins220-/-: embryonic day 13.5; Kidins220^tm1.2Fces/Kidins220^tm1.2Fces (more

)

Structure	Level	Pattern	Image	Note
TS21: brain	Absent		5-/-	As in wild type, no immunoreactive cells were present at this stage in the mutant.
TS21: forebrain	Absent		5-/-	As in wild type, no immunoreactive cells were present at this stage in the mutant.

6Ba ©

6Bb ©

6Bc ©

Specimen 6Ba: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: telencephalon	Absent		6Bb , 6Ba
TS23: retina	Absent		6Ba , 6Bc

6Ba' ©

6Bb' ©

6Bc' ©

Specimen 6Ba': embryonic day 15.5; Kidins220^tm1.2Fces/Kidins220^tm1.2Fces (more

)

Structure	Level	Pattern	Image	Note
TS23: telencephalon	Present	Clusters	6Ba' , 6Bb'	Immunopositive cell clusters were detected in the neuroepithelium adjacent to the lateral ventricle.
TS23: retina	Present	Clusters	6Bc' , 6Ba'

6Ca ©

6Cb ©

Specimen 6Ca: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: thalamus	Absent		6Ca , 6Cb

6Ca' ©

6Cb' ©

Specimen 6Ca': embryonic day 15.5; Kidins220^tm1.2Fces/Kidins220^tm1.2Fces (more

)

Structure	Level	Pattern	Image	Note
TS23: thalamus	Present		6Ca' , 6Cb'

7Ca ©

Specimen 7Ca: embryonic day 18.5; Kidins220^tm1.1Fces/Kidins220^tm1.1Fces, Tg(Nes-cre)1Kln/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: brain subventricular zone	Absent		7Ca

7Cb ©

Specimen 7Cb: embryonic day 18.5; Kidins220^tm1.1Fces/Kidins220^tm1.1Fces, Tg(Nes-cre)1Kln/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: hippocampus	Absent		7Cb

7Cc ©

Specimen 7Cc: embryonic day 18.5; Kidins220^tm1.1Fces/Kidins220^tm1.1Fces, Tg(Nes-cre)1Kln/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: nucleus reuniens	Absent		7Cc

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