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Gene Expression Data
Assay Details
Assay
Reference: J:327901 Ye Q, et al., Understanding the development of oral epithelial organs through single cell transcriptomic analysis. Development. 2022 Aug 15;149(16):dev200539
Assay type: RNA in situ
MGI Accession ID: MGI:7615292
Gene symbol: Dmrt2
Gene name: doublesex and mab-3 related transcription factor 2
Probe: Mm-Dmrt2 (564931)
Probe preparation: Antisense DNA
Visualized with: Fluorescence
Results
Specimen 7A: embryonic day 9.5 (more )
Note: Triple labeled: cyan - Dmrt2; green - Cxcl14 (assay MGI:7615293); red - Irx1 (assay MGI:7615072).
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component Trace 7A , 7A'

Specimen 7B: embryonic day 10.0 (more )
Note: Triple labeled: cyan - Dmrt2; green - Cxcl14 (assay MGI:7615293); red - Irx1 (assay MGI:7615072).
Structure Level Pattern Image Note
TS16: 1st branchial arch mandibular component Trace 7B , 7B'

Specimen 7C: embryonic day 10.5 (more )
Note: Triple labeled: cyan - Dmrt2; green - Cxcl14 (assay MGI:7615293); red - Irx1 (assay MGI:7615072).
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component Trace 7C , 7C'

Specimen 7D: embryonic day 11.0 (more )
Note: Triple labeled: cyan - Dmrt2; green - Cxcl14 (assay MGI:7615293); red - Irx1 (assay MGI:7615072).
Structure Level Pattern Image Note
TS18: 1st branchial arch mandibular component ectoderm Present Regionally restricted 7D' lower left , 7D' lower right , 7D , 7D' Expression emerged in the ectoderm between the dental lamina and the endoderm.

Specimen 7E: embryonic day 12.0 (more )
Note: Triple labeled: cyan - Dmrt2; green - Cxcl14 (assay MGI:7615293); red - Irx1 (assay MGI:7615072).
Structure Level Pattern Image Note
TS20: mandibular process epithelium Present Regionally restricted 7E'' , 7E , 7E' Expression was detected in the zone posterior to the dental epithelium. Some overlap with Irx1 expression was observed at the boundary (2-4 cells) of the posterior region and dental region.

Specimen S6G right: embryonic day 12.0 (more )
Note: Double labeled: cyan - Dmrt2; red - Zfp750 (assay MGI:7615304).
Structure Level Pattern Image Note
TS20: oral region epithelium Present Regionally restricted S6G' left , S6G' right , S6G right Expression was detected in the posterior oral epithelium.
TS20: periderm Present Regionally restricted S6G' left , S6G right , S6G' right Expression overlapped with Zfp750 staining in the periderm.

Specimen S9B: embryonic day 10.5 (more )
Note: Double labeled: cyan - Dmrt2; red - Shh (assay MGI:7615298).
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component endoderm Present S9B
TS17: 1st branchial arch mandibular component ectoderm Absent S9B

Specimen S9C E11.0: embryonic day 11.0 (more )
Note: Triple labeled: cyan - Dmrt2; red - Irx1 (assay MGI:7615072); green - Rxfp1 (assay MGI:7623179).
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component ectoderm Present Regionally restricted S9C E11.0 upper Expression emerged in the ectoderm between the dental lamina and the endoderm.

Specimen S9C E11.5: embryonic day 11.5 (more )
Note: Triple labeled: cyan - Dmrt2; red - Irx1 (assay MGI:7615072); green - Rxfp1 (assay MGI:7623179).
Structure Level Pattern Image Note
TS19: mandibular process Present Regionally restricted S9C E11.5 upper Expression was detected in the posterior epithelium.

Specimen S9C E12.0: embryonic day 12.0 (more )
Note: Triple labeled: cyan - Dmrt2; red - Irx1 (assay MGI:7615072); green - Rxfp1 (assay MGI:7623179).
Structure Level Pattern Image Note
TS20: mandibular process epithelium Present Regionally restricted S9C E12.0 upper Expression was detected in the posterior epithelium.

Specimen S9C E12.5: embryonic day 12.5 (more )
Note: Triple labeled: cyan - Dmrt2; red - Irx1 (assay MGI:7615072); green - Rxfp1 (assay MGI:7623179).
Structure Level Pattern Image Note
TS20: mandibular process epithelium Present Regionally restricted S9C E12.5 upper Expression was detected in the posterior epithelium.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory