Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:213418
Li D, et al., Formation of proximal and anterior limb skeleton requires early function of Irx3 and Irx5 and is negatively regulated by Shh signaling. Dev Cell. 2014 Apr 28;29(2):233-40
|
|
Assay type:
|
In situ reporter (knock in)
|
|
MGI Accession ID:
|
MGI:7615126
|
|
Gene symbol:
|
Irx3
|
|
Gene name:
|
Iroquois related homeobox 3
|
|
Reporter:
|
lacZ
|
|
|
Direct Detection
|
|
|
Results
|
Specimen
1B:
embryonic day 8.5; Irx3tm1Hui/Irx3 +
(more )
Specimen
1B:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
|
Mutant Allele(s):
|
Irx3tm1Hui/Irx3+
|
|
Age:
|
embryonic day 8.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
1C:
embryonic day 9.5; Irx3tm1Hui/Irx3 +
(more )
Specimen
1C:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
|
Mutant Allele(s):
|
Irx3tm1Hui/Irx3+
|
|
Age:
|
embryonic day 9.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS15: embryo |
Present |
|
1C
|
Expression domains overlapped with that of Irx5.
|
Specimen
1E:
embryonic day 10.0; Irx3tm1Hui/Irx3 +
(more )
Specimen
1E:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
|
Mutant Allele(s):
|
Irx3tm1Hui/Irx3+
|
|
Age:
|
embryonic day 10.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS16: hindlimb bud |
Present |
Regionally restricted |
1E
|
Expressed in the anterior region.
|
Specimen
1F:
embryonic day 10.5; Irx3tm1Hui/Irx3 +
(more )
Specimen
1F:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
|
Mutant Allele(s):
|
Irx3tm1Hui/Irx3+
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: hindlimb bud |
Present |
Regionally restricted |
1F
|
Expressed in the anterior region.
|
Specimen
1G:
embryonic day 12.5; Irx3tm1Hui/Irx3 +
(more )
Specimen
1G:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
|
Mutant Allele(s):
|
Irx3tm1Hui/Irx3+
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: hindlimb |
Present |
Regionally restricted |
1G
|
Expressed in the proximal-anterior limb.
|
|