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Gene Expression Data
Assay Details
Assay
Reference: J:261937 Mirzamohammadi F, et al., Distinct molecular pathways mediate Mycn and Myc-regulated miR-17-92 microRNA action in Feingold syndrome mouse models. Nat Commun. 2018 Apr 10;9(1):1352
Assay type: RNA in situ
MGI Accession ID: MGI:7611990
Gene symbol: Mir17
Gene name: microRNA 17
Probe: mmu-miR-17-5p (YD00615470-BCG)
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen S2 Ctrl: embryonic day 14.5; Mycntm1Psk/Mycntm1Psk (more )
Structure Cell Type Level Pattern Image Note
TS22: metacarpus cartilage condensation chondrocyte Present S2_miR-17-5p Ctrl higher mag , S2_miR-17-5p Ctrl
TS22: perichondrium perichondrial fibroblast Present S2_miR-17-5p Ctrl higher mag , S2_miR-17-5p Ctrl

Specimen S2 cKO: embryonic day 14.5; Mycntm1Psk/Mycntm1Psk, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS22: metacarpus cartilage condensation chondrocyte Weak S2_miR-17-5p cKO , S2_miR-17-5p cKO higher mag Expression was reduced in the Mycn-deficient limbs.
TS22: perichondrium perichondrial fibroblast Weak S2_miR-17-5p cKO higher mag , S2_miR-17-5p cKO Expression was reduced in the Mycn-deficient limbs.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory