About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:320376 Kleijer KTE, et al., Structural abnormalities in the primary somatosensory cortex and a normal behavioral profile in Contactin-5 deficient mice. Cell Adh Migr. 2018 Jan 2;12(1):5-18
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7611709
Gene symbol: Cntn5
Gene name: contactin 5
Antibody: Anti-Cntn5 H4543
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1D: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: inferior colliculus Present 1D
Specimen 1E: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: superior olivary nucleus Present 1E
Specimen 1F: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: anterior dorsal thalamic nucleus Present 1F
TS28: anterior ventral thalamic nucleus Present 1F
TS28: lateral thalamic group Present Regionally restricted 1F Expression was in laterodorsal thalamic nucleus.
Specimen 1G: postnatal day 7; Cntn5tm1Kwat/Cntn5tm1Kwat (more )
Structure Level Pattern Image Note
TS28: inferior colliculus Weak 1G Mild background staining was noted in the mutant inferior colliculus.
Specimen 1H: postnatal day 7; Cntn5tm1Kwat/Cntn5tm1Kwat (more )
Structure Level Pattern Image Note
TS28: superior olivary nucleus Absent 1H
Specimen 1I: postnatal day 7; Cntn5tm1Kwat/Cntn5tm1Kwat (more )
Structure Level Pattern Image Note
TS28: anterior dorsal thalamic nucleus Absent 1I
TS28: anterior ventral thalamic nucleus Absent 1I
TS28: lateral thalamic group Absent 1I
Specimen 2A: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus molecular layer Present 2A
TS28: hippocampus molecular layer Present 2A
Specimen 2D: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cortical layer IV Present Non-Uniform 2E , 2D
TS28: cortical layer V Present Non-Uniform 2E , 2D
TS28: primary somatosensory cortex Present Regionally restricted 2D , 2E Expression of the protein seems to most prominently localize in the septa between the barrels.
Specimen 2G: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: mammillary body Strong 2G
TS28: mammillothalamic tract of hypothalamus Strong 2G
Specimen Table 1: postnatal day 7 (more )
Note: + coded as 'present'; ++ coded as 'strong'; +/- coded as 'weak'.
Structure Level Pattern Image Note
TS28: accessory olfactory bulb mitral cell layer Present
TS28: cortical layer IV Present
TS28: cortical layer V Present
TS28: entorhinal cortex Present
TS28: main olfactory bulb glomerular layer Present
TS28: main olfactory bulb granule cell layer Present
TS28: main olfactory bulb mitral cell layer Present
TS28: piriform cortex Strong
TS28: hippocampal formation Present Regionally restricted Expression was present in parasubiculum, postsubiculum, and presubiculum.
TS28: dentate gyrus molecular layer Present
TS28: subiculum Present
TS28: hippocampus molecular layer Present Non-Uniform Expression was present in the CA1 lacunosum moleculare and weak in the CA2 lacunosum moleculare.
TS28: hippocampus stratum lucidum Present Regionally restricted Expression was present in the CA3 stratum lucidum.
TS28: amygdala Present
TS28: caudate-putamen Present
TS28: lateral dorsal thalamic nucleus Strong
TS28: anterior medial thalamic nucleus Present
TS28: anterior ventral thalamic nucleus Present
TS28: central lateral thalamic nucleus Present
TS28: lateral geniculate nucleus Present
TS28: lateral posterior thalamic nucleus Present
TS28: medial dorsal thalamic nucleus Present
TS28: medial geniculate nucleus Present
TS28: posterior thalamic group Present
TS28: thalamus Weak Entry in table Thalamus: Other +/-.
TS28: inferior colliculus Strong
TS28: superior olivary nucleus Strong
TS28: supramammillary nucleus Present
TS28: zona incerta Present
TS28: lateral mammillary nucleus Strong
TS28: medial mammillary nucleus Strong
TS28: hypothalamus Weak Diffuse Entry in table Hypothalamus: Diffuse +/-.
TS28: cerebellum Purkinje cell layer Present
Specimen Table 2: postnatal day 7 (more )
Note: + coded as 'present'; ++ coded as 'strong'.
Structure Level Pattern Image Note
TS28: cerebral internal capsule Present
TS28: external capsule Present
TS28: anterior commissure Present The anterior commissure and intrabulbar anterior commissure were listed in the table with positive expression.
TS28: hippocampal commissure Present Both ventral and dorsal hippocampal commissure had positive expression.
TS28: fimbria hippocampus Strong
TS28: mammillothalamic tract of hypothalamus Strong
TS28: thalamocortical tract Strong
TS28: cerebral peduncle Present
TS28: corpus callosum Present
TS28: fasciculus retroflexus Present
TS28: fornix Present
TS28: medial lemniscus Present
TS28: principal mammillary tract Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory