Cntn5^tm1Kwat
Targeted Allele Detail

Summary

• Symbol: Cntn5^tm1Kwat
• Name: contactin 5; targeted mutation 1, Kazutada Watanabe
• MGI ID: MGI:3051963
• Synonyms: NB-2^-
• Gene: Cntn5 Location: Chr9:9660896-10904780 bp, - strand Genetic Position: Chr9, 2.46 cM
• Alliance: Cntn5^tm1Kwat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:89425
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to replace approximately 400 bp from the ATG in exon 2 to intron 2 with a tau-LacZ-neo cassette. Southern blot and PCR confirmed recombination. No protein was found in mutants by Western blot and X-gal staining demonstrated LacZ expression in mutant brains. (J:89425)

Expression

In Mice Carrying this Mutation:

16 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cntn5 Mutation: 67 strains or lines available

References

• Original: J:89425 Li H, et al., Aberrant responses to acoustic stimuli in mice deficient for neural recognition molecule NB-2. Eur J Neurosci. 2003 Mar;17(5):929-36
• All: 6 reference(s)