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Gene Expression Data
Assay Details
Assay
Reference: J:309183 Gomes AL, et al., RINT1 Loss Impairs Retinogenesis Through TRP53-Mediated Apoptosis. Front Cell Dev Biol. 2020;8:711
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7610732
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-caspase-3 (clone C92-605)
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 3E Ctrl: embryonic day 15.5; Rint1tm1.1Pof/Rint1tm1.1Pof (more )
Structure Level Pattern Image Note
TS23: retina layer Present Single cells 3E Ctrl
Specimen 3E cKO: embryonic day 15.5; Rint1tm1.1Pof/Rint1tm1.1Pof, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: retina layer Present Single cells 3E cKO An increase of positive cells was observed in the mutant (quantified in Fig 3F).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory