Rint1^tm1.1Pof
Targeted Allele Detail

Summary

• Symbol: Rint1^tm1.1Pof
• Name: RAD50 interactor 1; targeted mutation 1.1, Pierre-Olivier Frappart
• MGI ID: MGI:5829713
• Synonyms: Rint1^F, Rint1 floxed
• Gene: Rint1 Location: Chr5:23992709-24025367 bp, + strand Genetic Position: Chr5, 10.45 cM
• Alliance: Rint1^tm1.1Pof page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:239805
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 3 was floxed. Flp-mediated recombination removed the neomycin resistance cassette inserted upstream of exon 3. (J:239805)

Expression

In Mice Carrying this Mutation:

12 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rint1 Mutation: 37 strains or lines available

References

• Original: J:239805 Grigaravicius P, et al., Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibition in the brain. Cell Death Differ. 2016 Mar;23(3):454-68
• All: 2 reference(s)