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Gene Expression Data
Assay Details
Assay
Reference: J:309183 Gomes AL, et al., RINT1 Loss Impairs Retinogenesis Through TRP53-Mediated Apoptosis. Front Cell Dev Biol. 2020;8:711
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7610731
Gene symbol: Chek1
Gene name: checkpoint kinase 1
Antibody: anti-pChk1
Detection system: Secondary antibody coupled to Cy3
Assay notes: This antibody recognizes the phosphorylated form of the protein.
Results
Specimen 2I Ctrl: embryonic day 14.5; Rint1tm1.1Pof/Rint1tm1.1Pof (more )
Structure Level Pattern Image Note
TS22: neural retina Absent 2I Ctrl
Specimen 2I cKO: embryonic day 14.5; Rint1tm1.1Pof/Rint1tm1.1Pof, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: neural retina Present 2I cKO An increase of positive cells was observed in the mutant (quantified in Fig 2J).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory