Gene Expression Data
Assay Details
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Assay
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Reference:
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J:146220
Maclean G, et al., Genetic disruption of CYP26B1 severely affects development of neural crest derived head structures, but does not compromise hindbrain patterning. Dev Dyn. 2009 Mar;238(3):732-45
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7595647
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Gene symbol:
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Sox10
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Gene name:
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SRY (sex determining region Y)-box 10
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Probe:
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Sox10 probe
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
6M:
embryonic day 8.5-9.0
(more  )
Specimen
6M:
(close  )
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Genetic Background:
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involves: 129S2/SvPas
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Age:
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embryonic day 8.5-9.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS13: neural crest |
migratory neural crest cell |
Present |
Regionally restricted |
6M
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Sox10 expression was analyzed as a marker of r2- and r4-derived neural crest cells.
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Specimen
6N:
embryonic day 8.5-9.0
(more )
Specimen
6N:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Age:
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embryonic day 8.5-9.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS13: neural crest |
migratory neural crest cell |
Present |
Regionally restricted |
6N
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Sox10 expression was analyzed as a marker of r2- and r4-derived neural crest cells.
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Specimen
6O:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Cyp26b1tm1.1Ptk/Cyp26b1tm1.1Ptk
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Age:
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embryonic day 8.5-9.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS13: neural crest |
migratory neural crest cell |
Present |
Regionally restricted |
6O
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No difference in expression was observed between Cyp26b1-/- and wild type embryos.
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Specimen
6P:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Cyp26b1tm1.1Ptk/Cyp26b1tm1.1Ptk
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Age:
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embryonic day 8.5-9.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS13: neural crest |
migratory neural crest cell |
Present |
Regionally restricted |
6P
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No difference in expression was observed between Cyp26b1-/- and wild type embryos.
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Analysis Tools