About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:333825 Lorenzana-Carrillo MA, et al., TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure. Sci Transl Med. 2022 Nov 2;14(669):eabm3565
Assay type: Western blot
MGI Accession ID: MGI:7581044
Gene symbol: Pkm
Gene name: pyruvate kinase, muscle
Antibody: PKM2(phospho-Ser37) Antibody #11456
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: The antibody used recognizes the phosphorylated form of the protein.
Results Image: 1C S37PPKM2
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
Fetal E18.0 (a) TS26: heart Present C57BL/6N Not Specified
Adult P m 3 TS28: heart Present (b) C57BL/6N Not Specified
Notes:
(a) Age of embryo at noon of plug day not specified in reference.
(b) Higher expression compared with that of the fetal.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/30/2025
MGI 6.24
The Jackson Laboratory