Lef1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:335190 Geng S, et al., Balancing WNT signalling in early forebrain development: The role of LRP4 as a modulator of LRP6 function. Front Cell Dev Biol. 2023;11:1173688
Assay type:	RNA in situ
MGI Accession ID:	MGI:7580707
Gene symbol:	Lef1
Gene name:	lymphoid enhancer binding factor 1

Probe:	Lef1 probe
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

S5A ©

S5a' ©

Specimen S5A,a': embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: future forebrain	Present	Regionally restricted	S5a' , S5A	Expression in dorsal lateral region.

S5B ©

S5b' ©

Specimen S5B,b': embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: future forebrain	Present	Regionally restricted	S5B , S5b'	Expression in dorsal lateral region.

S5C ©

S5c' ©

Specimen S5C,c': embryonic day 9.5; Lrp4^mitt/Lrp4^mitt (more

)

Structure	Level	Pattern	Image	Note
TS15: future forebrain	Present	Regionally restricted	S5c' , S5C	Expression not altered compared to wild type.

S5D ©

S5d' ©

Specimen S5D,d': embryonic day 9.5; Lrp4^mitt/Lrp4^mitt (more

)

Structure	Level	Pattern	Image	Note
TS15: future forebrain	Present	Regionally restricted	S5D , S5d'	Expression not altered compared to wild type.

S5E ©

S5e' ©

Specimen S5E,e': embryonic day 9.5; Lrp6^Gt(Ex187)Byg/Lrp6^Gt(Ex187)Byg (more

)

Structure	Level	Pattern	Image	Note
TS15: future forebrain	Weak		S5e' , S5E	Great reduction of expression in neuroepithelium

S5F ©

S5f' ©

Specimen S5F,f': embryonic day 9.5; Lrp6^Gt(Ex187)Byg/Lrp6^Gt(Ex187)Byg (more

)

Structure	Level	Pattern	Image	Note
TS15: future forebrain	Weak		S5f' , S5F	Great reduction of expression in neuroepithelium

S5G ©

S5g' ©

Specimen S5G,g': embryonic day 9.5; Lrp4^mitt/Lrp4^mitt, Lrp6^Gt(Ex187)Byg/Lrp6^Gt(Ex187)Byg (more

)

Structure	Level	Pattern	Image	Note
TS15: future forebrain	Strong	Regionally restricted	S5G , S5g'	Elevated levels of expression, Expression in neuroepithelial excrescences.

S5H ©

S5h' ©

Specimen S5H,h': embryonic day 9.5; Lrp4^mitt/Lrp4^mitt, Lrp6^Gt(Ex187)Byg/Lrp6^Gt(Ex187)Byg (more

)

Structure	Level	Pattern	Image	Note
TS15: future forebrain	Strong	Regionally restricted	S5H , S5h'	Elevated levels of expression, Expression in neuroepithelial excrescences.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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