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Gene Expression Data
Assay Details
Assay
Reference: J:229008 Escot S, et al., Disruption of CXCR4 signaling in pharyngeal neural crest cells causes DiGeorge syndrome-like malformations. Development. 2016 Feb 15;143(4):582-8
Assay type: RNA in situ
MGI Accession ID: MGI:7580638
Gene symbol: Cxcl12
Gene name: C-X-C motif chemokine ligand 12
Probe: Sdf-1 probe
Probe preparation: Antisense RNA
Results
Specimen 1Aa: embryonic day 9.5 (more )
Structure Cell Type Level Pattern Image Note
TS15: branchial arch ectoderm Present Regionally restricted 1Aa Expression is in proximity of migrating neural crest cells.
TS15: branchial arch endoderm Present Regionally restricted 1Aa Expression is in proximity of migrating neural crest cells.
TS15: migrating neural crest migratory neural crest cell Present 1Aa
Specimen 1Ae: embryonic day 9.5 (more )
Structure Cell Type Level Pattern Image Note
TS15: 2nd branchial arch ectoderm Present Regionally restricted 1Ae Expression is in proximity of migrating neural crest cells.
TS15: 2nd branchial arch endoderm Present Regionally restricted 1Ae Expression is in proximity of migrating neural crest cells.
TS15: migrating neural crest migratory neural crest cell Present 1Ae
Specimen 1Ba: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 2nd branchial arch mesenchyme Present 1Ba
TS17: 3rd branchial arch mesenchyme Present 1Ba
Specimen 1Ca: embryonic day 9.5 (more )
Structure Cell Type Level Pattern Image Note
TS15: branchial arch Present Regionally restricted 1Ca Expression is in proximity of migrating neural crest cells.
TS15: migrating neural crest migratory neural crest cell Present 1Ca
Specimen 1Cb: embryonic day 9.5; Tbx1tm1Pa/Tbx1tm1Pa (more )
Structure Level Pattern Image Note
TS15: branchial arch Weak 1Cb
Specimen 1Ce: embryonic day 9.5 (more )
Structure Cell Type Level Pattern Image Note
TS15: 2nd branchial arch ectoderm Present Regionally restricted 1Ce Expression is in proximity of migrating neural crest cells.
TS15: 2nd branchial arch endoderm Present Regionally restricted 1Ce Expression is in proximity of migrating neural crest cells.
TS15: migrating neural crest migratory neural crest cell Present 1Ce
Specimen 1Cf: embryonic day 9.5; Tbx1tm1Pa/Tbx1tm1Pa (more )
Structure Level Pattern Image Note
TS15: branchial arch Weak 1Cf
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory