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Gene Expression Data
Assay Details
Assay
Reference: J:190564 Tavares AL, et al., Ectodermal-derived Endothelin1 is required for patterning the distal and intermediate domains of the mouse mandibular arch. Dev Biol. 2012 Nov 1;371(1):47-56
Assay type: RNA in situ
MGI Accession ID: MGI:7580429
Gene symbol: Dlx2
Gene name: distal-less homeobox 2
Probe: Dlx2 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5A: embryonic day 10.5; Edn1tm1Ywa/Edn1tm1Ywa (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mesenchyme Present Regionally restricted 5A Expression in proximal mandibular arch mesenchyme.
TS17: 1st branchial arch ectoderm Present Regionally restricted 5A Expression along ectoderm overlying distal mandibular arch.
Specimen 5F: embryonic day 10.5; Edn1tm1Ywa/Edn1tm1Ywa, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch mesenchyme Present Regionally restricted 5F Mesenchymal expression was not upregulated distally.
TS17: 1st branchial arch ectoderm Present Regionally restricted 5F Expression disrupted along most of distal ectoderm of mandibular pharyngeal arch.
Specimen 5K: embryonic day 10.5; Edn1tm1Ywa/Edn1tm1Ywa, Tg(Tcfap2a-cre)1Will/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch Present 5K Expression unaffected compared to control.
Specimen 5P: embryonic day 10.5; Edn1tm1Ywa/Edn1tm1Ywa, Myf5tm3(cre)Sor/Myf5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch Present 5P Expression unaffected compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory