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Gene Expression Data
Assay Details
Assay
Reference: J:181601 Bassett EA, et al., Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Dev Dyn. 2012 Apr;241(4):814-29
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7579009
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti-Pax6
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 4D: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: neural retina Strong Regionally restricted 4D Strongly immunoreactive cells in the neuroblast layer were presumptive amacrine or horizontal cells.
TS27: retina inner nuclear layer amacrine cell Strong 4D
Specimen 4E: postnatal day 0 (more )
Note: Double labeled: red - Pax6; green - Tfap2c (assay MGI:7579003).
Structure Cell Type Level Pattern Image Note
TS27: neural retina Strong Regionally restricted 4E Strongly immunoreactive cells in the neuroblast layer were presumptive amacrine or horizontal cells. Staining overlapped with Tfap2c-positive cells.
TS27: retina inner nuclear layer amacrine cell Strong 4E Staining overlapped with Tfap2c-positive cells.
Specimen 4F: postnatal day 7 (more )
Note: Double labeled: red - Pax6; green - Tfap2c (assay MGI:7579003).
Structure Level Pattern Image Note
TS28: neural retina Present Regionally restricted 4F Staining overlapped with Tfap2c-positive cells.
Specimen 4G: postnatal adult (more )
Note: Double labeled: red - Pax6; green - Tfap2c (assay MGI:7579003).
Structure Level Pattern Image Note
TS28: neural retina Present Regionally restricted 4G Staining overlapped with Tfap2c-positive cells.
Specimen 8A: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: neural retina amacrine cell Present 8A Pax6 is a pan-amacrine cell marker.
Specimen 8B: postnatal day 0; Tfap2atm1Hsv/Tfap2atm1.1Hsv, Tfap2btm1Rbu/Tfap2btm1Rbu, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: neural retina amacrine cell Present 8B Immunostaining in the mutant was comparable to control.
Specimen not shown E16.5 control: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: neural retina amacrine cell Present
Specimen not shown E16.5 mutant: embryonic day 16.5; Tfap2atm1Hsv/Tfap2atm1.1Hsv, Tfap2btm1Rbu/Tfap2btm1Rbu, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS24: neural retina amacrine cell Present Immunostaining in the mutant was comparable to control.
Specimen not shown E18.5 control: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: neural retina amacrine cell Present
Specimen not shown E18.5 mutant: embryonic day 18.5; Tfap2atm1Hsv/Tfap2atm1.1Hsv, Tfap2btm1Rbu/Tfap2btm1Rbu, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: neural retina amacrine cell Present Immunostaining in the mutant was comparable to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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