About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:181601 Bassett EA, et al., Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Dev Dyn. 2012 Apr;241(4):814-29
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7578999
Gene symbol: Prox1
Gene name: prospero homeobox 1
Antibody: anti-Prox1
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 2E: embryonic day 16.5 (more )
Note: Double labeled: red - Prox1; green - Tfap2a (assay MGI:7578959).
Structure Cell Type Level Pattern Image Note
TS24: neural retina retina horizontal cell Present 2E Expression was detected in horizontal cells that co-express Tfap2a.
Specimen 3E: embryonic day 16.5 (more )
Note: Double labeled: red - Prox1; green - Tfap2c (assay MGI:7579003).
Structure Cell Type Level Pattern Image Note
TS24: neural retina retina horizontal cell Present 3E No co-expression with Tfap2c was observed.
Specimen not shown Tcfap2a/b E18.5: embryonic day 18.5; Tfap2atm1Hsv/Tfap2atm1.1Hsv, Tfap2btm1Rbu/Tfap2btm1Rbu, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: neural retina Ambiguous Regionally restricted Staining was not detected in horizontal cells of the outer retina in the double mutant, which suggested a near loss of horizontal cells.
Specimen not shown Tcfap2a/b P0: postnatal day 0; Tfap2atm1Hsv/Tfap2atm1.1Hsv, Tfap2btm1Rbu/Tfap2btm1Rbu, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: neural retina Ambiguous Regionally restricted Staining was not detected in horizontal cells of the outer retina in the double mutant, which suggested a near loss of horizontal cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory