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Gene Expression Data
Assay Details
Assay
Reference: J:93057 Schuurmans C, et al., Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways. EMBO J. 2004 Jul 21;23(14):2892-902
Assay type: RNA in situ
MGI Accession ID: MGI:7578971
Gene symbol: Tbr1
Gene name: T-box brain transcription factor 1
Probe: Tes-56
Probe preparation: Antisense RNA
Results
Specimen 2C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex intermediate zone Present 2C
TS23: cortical plate Present 2C

Specimen 2D: embryonic day 15.5; Neurog2tm2Fgu/Neurog2tm2Fgu (more )
Structure Level Pattern Image Note
TS23: cortical plate Present Regionally restricted 2D A correctly specified upper layer above distinct gaps in lower layer expression was seen.
TS23: cerebral cortex intermediate zone Present 2D

Specimen 6G: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex intermediate zone Present 6G
TS23: cortical plate Present 6G

Specimen 6H: embryonic day 15.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS23: cerebral cortex intermediate zone Present 6H Reduced expression throughout the layer, compared with the wild-type.
TS23: cortical plate Present 6H Reduced expression throughout the layer, compared with the wild-type.

Specimen 6I: embryonic day 15.5; Nr2e1tm1Rtyu/Nr2e1tm1Rtyu, Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS23: cerebral cortex intermediate zone Present 6I Reduced expression throughout the layer, compared with the wild-type.
TS23: cortical plate Present 6I Reduced expression throughout the layer, compared with the wild-type.

Specimen 7I: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: neocortex Present Regionally restricted 7I Expressed in layer VI.

Specimen 7J: embryonic day 18.5; Nr2e1tm1Rtyu/Nr2e1tm1Rtyu (more )
Structure Level Pattern Image Note
TS26: neocortex Present Regionally restricted 7J Expressed in layer VI, similar as in the wild-type.

Specimen 7K: embryonic day 18.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS26: neocortex Present Regionally restricted 7K Expressed in layer VI, similar as in the wild-type.

Specimen 7L: embryonic day 18.5; Nr2e1tm1Rtyu/Nr2e1tm1Rtyu, Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS26: neocortex Present Regionally restricted 7L Expressed in layer VI, similar as in the wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory