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Gene Expression Data
Assay Details
Assay
Reference: J:93057 Schuurmans C, et al., Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways. EMBO J. 2004 Jul 21;23(14):2892-902
Assay type: RNA in situ
MGI Accession ID: MGI:7578968
Gene symbol: Dlx1
Gene name: distal-less homeobox 1
Probe: Dlx1 cDNA1
Probe preparation: Antisense RNA
Results
Specimen 2Q: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: cerebral cortex marginal layer cortical interneuron Present 2Q
TS23: cerebral cortex subventricular zone cortical interneuron Present 2Q

Specimen 2R: embryonic day 15.5; Neurog2tm2Fgu/Neurog2tm2Fgu (more )
Structure Cell Type Level Pattern Image Note
TS23: cerebral cortex marginal layer cortical interneuron Present 2R
TS23: cerebral cortex subventricular zone cortical interneuron Present 2R
TS23: cortical plate Present Clusters 2R Ectopic expression in lower region was seen, and was excluded from the more recently generated, superficial layer.

Specimen 2S: embryonic day 15.5; Neurog1tm1And/Neurog1tm1And, Neurog2tm2Fgu/Neurog2tm2Fgu (more )
Structure Cell Type Level Pattern Image Note
TS23: cerebral cortex marginal layer cortical interneuron Present 2S
TS23: cerebral cortex subventricular zone cortical interneuron Present 2S
TS23: cortical plate Present Clusters 2S Ectopic expression in lower region was seen, and was excluded from the more recently generated, superficial layer.

Specimen 2T: embryonic day 15.5; Ascl1tm1And/Ascl1tm1And, Neurog2tm2Fgu/Neurog2tm2Fgu (more )
Structure Level Pattern Image Note
TS23: cortical plate Present Regionally restricted 2T Ectopic expression was restricted to rostromedial domains.

Specimen 2X: embryonic day 15.5; Neurog2tm3(Ascl1)Fgu/Neurog2tm3(Ascl1)Fgu (more )
Structure Level Pattern Image Note
TS23: cortical plate Present Clusters 2X Ectopically expressed only in small clusters deep within the rostral region.

Specimen 3E: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex marginal zone cortical interneuron Present 3E
TS26: cortical plate cortical interneuron Present 3E
TS26: cerebral cortex cortical interneuron Present Regionally restricted 3E Expressed in the germinal zone.

Specimen 3F: embryonic day 18.5; Neurog2tm2Fgu/Neurog2tm2Fgu (more )
Structure Level Pattern Image Note
TS26: cerebral cortex intermediate zone Present Clusters 3F Expressed in ectopic clusters.

Specimen 3G: embryonic day 18.5; Neurog1tm1And/Neurog1tm1And, Neurog2tm2Fgu/Neurog2tm2Fgu (more )
Structure Level Pattern Image Note
TS26: cerebral cortex intermediate zone Present Clusters 3G Expressed in ectopic clusters.
TS26: cortical plate Present Clusters 3G Expressed in ectopic clusters in superficial region.

Specimen 3H: embryonic day 18.5; Neurog1tm1And/Neurog1tm1And, Neurog2tm2Fgu/Neurog2tm2Fgu (more )
Structure Level Pattern Image Note
TS26: cortical plate Present Regionally restricted 3H Expressed in ectopic clusters in superficial region.

Specimen 6M: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: cerebral cortex marginal layer cortical interneuron Present 6M Expressed in migrating interneurons.
TS23: cerebral cortex subventricular zone cortical interneuron Present 6M Expressed in migrating interneurons.

Specimen 6N: embryonic day 15.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS23: cerebral cortex intermediate zone Strong 6N A massive, ectopic upregulation of expression was seen, compared with the wild-type.
TS23: cerebral cortex subventricular zone Strong 6N A massive, ectopic upregulation of expression was seen, compared with the wild-type.

Specimen 6O: embryonic day 15.5; Nr2e1tm1Rtyu/Nr2e1tm1Rtyu, Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS23: cerebral cortex intermediate zone Strong 6O A massive, ectopic upregulation of expression was seen, compared with the wild-type.
TS23: cerebral cortex subventricular zone Strong 6O A massive, ectopic upregulation of expression was seen, compared with the wild-type.

Specimen 7E: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex marginal zone cortical interneuron Present 7E Expressed in migrating cortical interneurons.
TS26: cortical plate cortical interneuron Present 7E Expressed in migrating cortical interneurons.
TS26: cerebral cortex cortical interneuron Present Regionally restricted 7E Expressed in migrating cortical interneurons in the germinal zone.

Specimen 7F: embryonic day 18.5; Nr2e1tm1Rtyu/Nr2e1tm1Rtyu (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present Clusters 7F Expressed in small ectopic clusters in the germinal zone.

Specimen 7G: embryonic day 18.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present Regionally restricted 7G Expressed in a grossly expanded germinal zone, compared with the wild-type.

Specimen 7H: embryonic day 18.5; Nr2e1tm1Rtyu/Nr2e1tm1Rtyu, Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present Regionally restricted 7H Expressed in a grossly expanded germinal zone, compared with the wild-type.


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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory