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Gene Expression Data
Assay Details
Assay
Reference: J:292124 Terenzio M, et al., DYNLRB1 is essential for dynein mediated transport and neuronal survival. Neurobiol Dis. 2020 Jul;140:104816
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7578906
Gene symbol: Calca
Gene name: calcitonin/calcitonin-related polypeptide, alpha
Antibody: anti-CGRP (ab36001)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen 2E wild type: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion pain receptor cell Present 2E wild type CGRP Expression in nociceptive neurons.
Specimen 2E RNX3-Dynlrb1-/-: postnatal adult; Dynlrb1tm1c(EUCOMM)Wtsi/Dynlrb1tm1c(EUCOMM)Wtsi, Runx3tm6(EGFP/cre)Yg/Runx3+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion pain receptor cell Present 2E RNX3-Dynlrb1-/- CGRP Expression not different from wild type.
Specimen S2G wild type: postnatal adult (more )
Note: Double labeled: red - Calca; green - Tubb3 (assay MGI:7578907).
Structure Cell Type Level Pattern Image Note
TS28: foot skin pain receptor cell Present S2G wild type CGRP , S2G wild type merge Expression in nociceptive neurons.
Specimen S2G RNX3-Dynlrb1-/-: postnatal adult; Dynlrb1tm1c(EUCOMM)Wtsi/Dynlrb1tm1c(EUCOMM)Wtsi, Runx3tm6(EGFP/cre)Yg/Runx3+ (more )
Note: Conditional mutant. Double labeled: red - Calca; green - Tubb3 (assay MGI:7578907).
Structure Level Pattern Image Note
TS28: foot skin Present S2G RNX3-Dynlrb1-/- CGRP , S2G RNX3-Dynlrb1-/- merge No significant difference compared to control.,
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
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