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Slc17a8tm1(cre)Hze
Targeted Allele Detail
Summary
Symbol: Slc17a8tm1(cre)Hze
Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8; targeted mutation 1, Hongkui Zeng
MGI ID: MGI:7571433
Synonyms: Slc17a8-IRES2-Cre-neo
Gene: Slc17a8  Location: Chr10:89409882-89457111 bp, - strand  Genetic Position: Chr10, 44.99 cM
Alliance: Slc17a8tm1(cre)Hze page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:146821
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Slc17a8tm1(cre)Hze expression driven by 1 gene
 
Mutation detailsThe targeting vector contains, from 5' to 3', a partial Slc17a8 sequence spanning intron 11, an frt3 site within Slc17a8 intron 11, a partial Slc17a8 exon 12 sequence up to and including the endogenous stop codon, an internal ribosome entry site 2 (IRES2) sequence (allows translation initiation in the middle of an mRNA sequence), a Cre recombinase gene, a bovine growth hormone polyA sequence, an AttB site, a PGK promoter-Neomycin resistance gene-PGK polyA cassette, an frt5 site, an mRNA splice acceptor sequence, the 3' portion of the hygromycin gene (Hygro2) with SV40 late polyA signal, and an AttP site. (J:146821)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Slc17a8 (mouse)
Summary of all recombinase alleles driven by Slc17a8.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc17a8 Mutation:  40 strains or lines available
References
Original:  J:146821 Allen Institute for Brain Science, Cre transgenes and knockin alleles created at the Allen Insitute for Brain Science (AIBS). MGI Direct Data Submission. 2009-04-06;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory