Hoxb6 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:239985 Casaca A, et al., Hoxb6 can interfere with somitogenesis in the posterior embryo through a mechanism independent of its rib-promoting activity. Development. 2016 Feb 01;143(3):437-48
Assay type:	RNA in situ
MGI Accession ID:	MGI:7570215
Gene symbol:	Hoxb6
Gene name:	homeobox B6

Probe:	Hoxb6 probe
Probe preparation:	Antisense labelled with digoxigenin RNA

Results

7A ©

Specimen 7A: embryonic day 8.5 (more

)

Structure	Level	Pattern	Image	Note
TS13: unsegmented mesenchyme	Weak		7A

7B ©

Specimen 7B: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: somite	Present		7B	With an anterior expression border at somite 12.
TS15: unsegmented mesenchyme	Present		7B

7C ©

Specimen 7C: embryonic day 10.5 (more

)

Structure	Level	Image	Note
TS17: somite	Present	7C	Retained the anterior boundary but became downregulated in more posterior areas (starting around somite 24).
TS17: unsegmented mesenchyme	Absent	7C
TS17: neural tube	Present	7C

7D ©

Specimen 7D: embryonic day 8.5 (more

)

Structure	Level	Pattern	Image	Note
TS13: neural plate	Present		7D
TS13: unsegmented mesenchyme	Present		7D

7E ©

Specimen 7E: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: tail unsegmented mesenchyme	Present		7E

7E' ©

Specimen 7E': embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: unsegmented mesenchyme	Present		7E'

7F ©

Specimen 7F: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Present		7F
TS17: unsegmented mesenchyme	Absent		7F

7F' ©

Specimen 7F': embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Present		7F'
TS17: somite	Ambiguous		7F'	Expression was downregulated (trace or absent) in more posterior areas.

8Ca ©

Specimen 8Ca: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: somite	Present		8Ca
TS15: unsegmented mesenchyme	Present		8Ca

8Cb ©

Specimen 8Cb: embryonic day 9.5; Hoxb6^em1Mllo/Hoxb6^em1Mllo (more

)

Structure	Level	Pattern	Image	Note
TS15: somite	Present		8Cb	Similar as in the wild-type.
TS15: unsegmented mesenchyme	Present		8Cb	Similar as in the wild-type.

8Cc ©

Specimen 8Cc: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: somite	Present		8Cc
TS15: unsegmented mesenchyme	Present		8Cc

8Cd ©

Specimen 8Cd: embryonic day 9.5; Hoxb6^em1Mllo/Hoxb6^em1Mllo (more

)

Structure	Level	Pattern	Image	Note
TS15: somite	Present		8Cd	Similar as in the wild-type.
TS15: unsegmented mesenchyme	Present		8Cd	Similar as in the wild-type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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