Hoxb6^em1Mllo
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hoxb6^em1Mllo
• Name: homeobox B6; endonuclease-mediated mutation 1, Moises Mallo
• MGI ID: MGI:7569262
• Synonyms: Hoxb6^{delta3'UTR412-474}
• Gene: Hoxb6 Location: Chr11:96183647-96192395 bp, + strand Genetic Position: Chr11, 59.82 cM
• Alliance: Hoxb6^em1Mllo page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting deleted a portion of the 3' UTR (412-474) encompassing Mir196 and Mir199 binding sites. (J:239985)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxb6 Mutation: 14 strains or lines available

References

• Original: J:239985 Casaca A, et al., Hoxb6 can interfere with somitogenesis in the posterior embryo through a mechanism independent of its rib-promoting activity. Development. 2016 Feb 01;143(3):437-48
• All: 1 reference(s)