Fabp7 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:67383 Britsch S, et al., The transcription factor Sox10 is a key regulator of peripheral glial development. Genes Dev. 2001 Jan 1;15(1):66-78
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7569222
Gene symbol:	Fabp7
Gene name:	fatty acid binding protein 7, brain

Antibody:	anti B-FABP
Detection system:	Secondary antibody coupled to Cy3

Results

4a ©

4b ©

Specimen 4a/b: embryonic day 11.5 (more

)
Note: Double labeled: red - Fabp7; green - Tubb3 (assay MGI:7569223).

Structure	Cell Type	Level	Pattern	Image	Note
TS19: dorsal root ganglion	glial cell	Strong		4a , 4b	peripheral glial cells
TS19: spinal nerve	glial cell	Strong		4a , 4b	peripheral glial cells

4c ©

4d ©

Specimen 4c/d: embryonic day 11.5; Sox10^Dom/Sox10^Dom (more

)
Note: Double labeled: red - Fabp7; green - Tubb3 (assay MGI:7569223).

Structure	Level	Pattern	Image	Note
TS19: dorsal root ganglion	Absent		4c , 4d
TS19: spinal nerve	Absent		4c , 4d

4e ©

4f ©

Specimen 4e/f: embryonic day 11.5; Erbb3^tm2Cbm/Erbb3^tm2Cbm (more

)
Note: Double labeled: red - Fabp7; green - Tubb3 (assay MGI:7569223).

Structure	Level	Pattern	Image	Note
TS19: dorsal root ganglion	Strong		4f , 4e
TS19: spinal nerve	Trace		4e , 4f	Very rare expression along the nerve.

5a ©

Specimen 5a: embryonic day 11.5; Sox10^tm1Weg/Sox10⁺ (more

)
Note: Double labeled: red - Fabp7; green - Sox10 reporter (assay MGI:7569230).

Structure	Cell Type	Level	Pattern	Image	Note
TS19: dorsal root ganglion	perineuronal satellite cell	Present		5a	Overlapped with beta-galactosidase staining to a large extent.

5c ©

Specimen 5c: embryonic day 12.5 (more

)
Note: Double labeled: red - Fabp7; green - Tubb3 (assay MGI:7569223).

Structure	Cell Type	Level	Pattern	Image	Note
TS20: dorsal root ganglion	perineuronal satellite cell	Present		5c
TS20: spinal nerve	perineuronal satellite cell	Present		5c

5f ©

Specimen 5f: embryonic day 11.5; Sox10^tm1Weg/Sox10^tm1Weg (more

)
Note: Double labeled: red - Fabp7; green - Sox10 reporter (assay MGI:7569230).

Structure	Level	Pattern	Image	Note
TS20: dorsal root ganglion	Absent		5f

5h ©

Specimen 5h: embryonic day 12.5; Sox10^Dom/Sox10^Dom (more

)
Note: Double labeled: red - Fabp7; green - Tubb3 (assay MGI:7569223).

Structure	Level	Pattern	Image	Note
TS20: dorsal root ganglion	Absent		5h
TS20: spinal nerve	Absent		5h

Specimen not shown: embryonic day 10.5 (more

)
Note: Double labeled: red - Fabp7.

Structure	Cell Type	Level	Note
TS17: dorsal root ganglion	migratory neural crest cell	Absent	No expression in neural crest cells along spinal nerves or in dorsal root ganglia.
TS17: migrating neural crest	migratory neural crest cell	Absent	No expression in neural crest cells along spinal nerves or in dorsal root ganglia.
TS17: spinal nerve	migratory neural crest cell	Absent	No expression in neural crest cells along spinal nerves or in dorsal root ganglia.

Specimen not shown: embryonic day 12.5 (more

)
Note: Double labeled: red - Fabp7.

Structure	Cell Type	Level	Pattern	Note
TS20: sympathetic ganglion	glial cell	Present		Not overlapping with neuron-specific staining.
TS20: cervical ganglion	perineuronal satellite cell	Present	Regionally restricted	Expressed in the superior cervical ganglion.
TS20: inferior vagus ganglion	perineuronal satellite cell	Present		nodose ganglion

Specimen not shown: embryonic day 12.5; Sox10^Dom/Sox10^Dom (more

)
Note: Double labeled: red - Fabp7.

Structure	Level	Pattern	Image	Note
TS20: cervical ganglion	Absent
TS20: inferior vagus ganglion	Absent

Specimen not shown: embryonic day 12.5; Erbb3^tm2Cbm/Erbb3^tm2Cbm (more

)
Note: Double labeled: red - Fabp7.

Structure	Cell Type	Level	Pattern	Image	Note
TS20: cervical ganglion	perineuronal satellite cell	Present
TS20: inferior vagus ganglion	perineuronal satellite cell	Present

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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