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Tg(H2-Ea-Cd40/Pdlim7)#Bshp
Transgene Detail
Summary
Symbol: Tg(H2-Ea-Cd40/Pdlim7)#Bshp
Name: transgene insertion #, Gail Bishop
MGI ID: MGI:7569167
Synonyms: mCD40-LMP1tg
Transgene: Tg(H2-Ea-Cd40/Pdlim7)#Bshp  Location: unknown  
Alliance: Tg(H2-Ea-Cd40/Pdlim7)#Bshp page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(H2-Ea-Cd40/Pdlim7)#Bshp expresses 2 genes
 
Tg(H2-Ea-Cd40/Pdlim7)#Bshp expression driven by 1 gene
 
Mutation detailsThis transgene encodes a chimeric molecule consisting of the extracellular and transmembrane domains of mouse Cd40, and the cytoplasmic tail of Pdlim7 (mCD40-LMP1 in paper).Several lines were generated but were not distinguished. (J:93594)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:93594 Stunz LL, et al., Expression of the cytoplasmic tail of LMP1 in mice induces hyperactivation of B lymphocytes and disordered lymphoid architecture. Immunity. 2004 Aug;21(2):255-66
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory