Gene Expression Data
Assay Details
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Assay
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Reference:
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J:242707
Ji F, et al., UCP2 Regulates Embryonic Neurogenesis via ROS-Mediated Yap Alternation in the Developing Neocortex. Stem Cells. 2017 Jun;35(6):1479-1492
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7569121
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Gene symbol:
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Tbr1
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Gene name:
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T-box brain transcription factor 1
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Antibody:
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anti-Tbr1
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Detection system:
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Secondary antibody coupled to Alexa Fluor 488
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Results
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Specimen
S3E fl/lf:
(close  )
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Genetic Background:
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involves: 129S6/SvEvTac
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Mutant Allele(s):
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Ucp2tm2.1Lowl/Ucp2tm2.1Lowl
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Age:
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embryonic day 15.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: cortical plate |
Present |
Regionally restricted |
S3E fl/fl Tbr1
,
S3E fl/fl (merged)
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Expression in deep layers of cortical plate.
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Specimen
S3E cko:
(close )
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Genetic Background:
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involves: 129S6/SvEvTac * C57BL/6 * SJL
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Mutant Allele(s):
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Tg(Nes-cre)1Kln/0
Ucp2tm2.1Lowl/Ucp2tm2.1Lowl
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Age:
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embryonic day 15.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: cortical plate |
Weak |
Regionally restricted |
S3E cko Tbr1
,
S3E cko (merged)
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Expression in deep layers of cortical plate reduced compared to control.
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Analysis Tools
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