Pax6 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:242707 Ji F, et al., UCP2 Regulates Embryonic Neurogenesis via ROS-Mediated Yap Alternation in the Developing Neocortex. Stem Cells. 2017 Jun;35(6):1479-1492
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7569118
Gene symbol:	Pax6
Gene name:	paired box 6

Antibody:	anti-Pax6
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

Specimen 4F fl/lf: embryonic day 15.0; Ucp2^tm2.1Lowl/Ucp2^tm2.1Lowl (more

)
Note: Double labeled: green - Pax6; red - BrdU.

Structure	Level	Pattern	Image	Note
TS23: neocortex	Present	Regionally restricted	4F fl/fl Pax6 , 4F fl/fl (merged)	Expression in cortical progenitor cells.

Specimen 4F cko: embryonic day 15.0; Tg(Nes-cre)1Kln/0, Ucp2^tm2.1Lowl/Ucp2^tm2.1Lowl (more

)
Note: Conditional mutant. Double labeled: green - Pax6; red - BrdU.

Structure	Level	Pattern	Image	Note
TS23: neocortex	Strong	Regionally restricted	4F cko Pax6 , 4F cko (merged)	Signficant increase in progenitor cells compared to control.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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