Ptch1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:321553 Neupane S, et al., O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development. Matrix Biol. 2022 Feb 12;
Assay type:	RNA in situ
MGI Accession ID:	MGI:7567571
Gene symbol:	Ptch1
Gene name:	patched 1

Results

Specimen 6A: embryonic day 14.5; Pofut2^tm2.1Bch/Pofut2⁺, Tg(Prrx1-cre)1Cjt/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS22: hindlimb	Present	Widespread	6A' , 6A	Expresson throughout limb.
TS22: tibia cartilage condensation	Present	Regionally restricted	6A' , 6A	Expression in proliferating, prehypertrohic and hypertrophic zones.
TS22: perichondrium	Strong		6A , 6A'

Specimen 6B: embryonic day 14.5; Pofut2^tm2.1Bch/Pofut2^tm2.2Bch, Tg(Prrx1-cre)1Cjt/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS22: hindlimb	Present	Widespread	6B , 6B'	Expresson throughout limb.
TS22: tibia cartilage condensation	Weak	Regionally restricted	6B' , 6B	Expression in proliferating, prehypertrohic and hypertrophic zones decreased compared to control.
TS22: perichondrium	Strong		6B' , 6B

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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