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Gene Expression Data
Assay Details
Assay
Reference: J:252112 Kim JJ, et al., Suppressor of fused controls cerebellar neuronal differentiation in a manner modulated by GLI3 repressor and Fgf15. Dev Dyn. 2018 Jan;247(1):156-169
Assay type: RNA in situ
MGI Accession ID: MGI:7565365
Gene symbol: Sufu
Gene name: SUFU negative regulator of hedgehog signaling
Probe: Sufu probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1C: embryonic day 13.5; Sufutm1Hui/Sufu+ (more )
Structure Level Pattern Image Note
TS21: cerebellum mantle layer Present 1C
TS21: cerebellum ventricular layer Present 1C

Specimen 1D: embryonic day 13.5; Sufutm1Hui/Sufutm1.1Hui, Tg(Fabp7-cre)1Htz/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: cerebellum mantle layer Present Regionally restricted 1D Some expression remained in cells that are located in the mantle zone close to the pial surface in the mutant.

Specimen 1E: postnatal day 14; Sufutm1Hui/Sufu+ (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 1G , 1E
TS28: cerebellum external granule cell layer Strong 1G , 1E

Specimen 1F: postnatal day 14; Sufutm1Hui/Sufutm1.1Hui, Tg(Fabp7-cre)1Htz/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebellum Present Regionally restricted 1F , 1H Expression was essentially undetectable in most cells except for presumptive granule cell precursors and the posterior edge of the cerebellum in mutant mice.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory