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Gene Expression Data
Assay Details
Assay
Reference: J:251853 Godbole G, et al., Novel functions of LHX2 and PAX6 in the developing telencephalon revealed upon combined loss of both genes. Neural Dev. 2017 Nov 15;12(1):19
Assay type: RNA in situ
MGI Accession ID: MGI:7564557
Gene symbol: Wnt8b
Gene name: wingless-type MMTV integration site family, member 8B
Probe: Wnt8b probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A Control: embryonic day 12.5; Lhx2tm1Dra/Lhx2+, Pax6Sey/Pax6+ (more )
Structure Level Pattern Image Note
TS20: cortical hem Present 1A Wnt8b
TS20: telencephalon Present Regionally restricted 1A Wnt8b Expression is in the hippocampal primordium.
Specimen 1B Pax6Sey/Sey: embryonic day 12.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 1B Wnt8b Expression is in the medial part.
Specimen 1C Lhx2 -/-: embryonic day 12.5; Lhx2tm1Dra/Lhx2tm1Dra (more )
Structure Level Pattern Image Note
TS20: cortical hem Present Regionally restricted 1C Wnt8b Expression is in the expanded hem, sparing some lateral tissue.
Specimen 1D Lhx2 -/-;Pax6Sey/Sey: embryonic day 12.5; Lhx2tm1Dra/Lhx2tm1Dra, Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 1D Wnt8b Expression is in the entire dorsal telencephalon.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory