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Gene Expression Data
Assay Details
Assay
Reference: J:47495 Yao J, et al., Combinatorial expression patterns of individual TLE proteins during cell determination and differentiation suggest non-redundant functions for mammalian homologs of Drosophila Groucho. Dev Growth Differ. 1998 Apr;40(2):133-46
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7564543
Gene symbol: Tle1
Gene name: transducin-like enhancer of split 1
Antibody: TLE1 antibody
Results
Specimen 6a: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 6a Expression was highest in the nuclei of cells in the ventral horn regions of the rostral neural tube. Weaker immunoreactivity was observed in apical cells of the dorsal neural tube.

Specimen 6b: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: diencephalon Present 6b
TS20: telencephalon ventricular layer Present Regionally restricted 6b Expression was detected in the ventricular zone lining the lateral ventricle.
TS20: cortical plate Present 6b

Specimen 6c: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present 6c
TS20: cortical plate Present 6c
TS20: cerebral cortex intermediate zone Absent 6c

Specimen 6d: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: choroid plexus Present 6d
TS22: telencephalon ventricular layer Present Regionally restricted 6d Expression was detected in the ventricular zone lining the posterior horn of the lateral ventricle.
TS22: cortical plate cerebral cortex neuron Present Regionally restricted 6d Expression was detected in the more external layers of neurons in the cortical plate.
TS22: cerebral cortex intermediate zone Weak 6d

Specimen 6e: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: cerebral cortex ventricular layer Present 6e
TS24: cerebral cortex subventricular zone Absent 6e
TS24: cerebral cortex intermediate zone Present 6e
TS24: cortical plate cerebral cortex neuron Present Regionally restricted 6e Expression was preferentially in more external layers of neurons.

Specimen 9a: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal cord ventricular layer Strong Regionally restricted 9a Expression was detected in the ventricular zone.
TS22: spinal cord Strong Regionally restricted 9a Expression was detected in the ventral half of the spinal cord.
TS22: dorsal root ganglion Strong 9a

Specimen 9b: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: dorsal root ganglion Present Non-Uniform 9b Immunoreactivity was observed predominantly in cells located around the periphery of the dorsal root ganglion.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory