Exosc1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:343201 Srinivasan S, et al., Exosome complex components 1 and 2 are vital for early mammalian development. Gene Expr Patterns. 2024 March;51:119346
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7564510
Gene symbol:	Exosc1
Gene name:	exosome component 1

Antibody:	anti-Exosc1 [EPR13526] (ab181108)
Detection system:	Secondary antibody coupled to Alexa Fluor

Results

5A ©

5A' ©

Specimen 5A: postnatal adult (more

)
Note: Triple labeled: red - Exosc1; green - Cdh1 (assay MGI:7564526); blue - DAPI.

Structure	Level	Pattern	Image	Note
TS28: ovary	Present	Ubiquitous	5A' , 5A	Expression is seen in all cells.
TS28: oocyte	Present	Ubiquitous	5A , 5A'
TS28: ovary follicle cell	Present	Ubiquitous	5A , 5A'	Expression is stronger in the granulosa cells.

5B ©

5B' ©

Specimen 5B: postnatal adult (more

)
Note: Triple labeled: red - Exosc1; green - Cdh1 (assay MGI:7564526); blue - DAPI.

Structure	Level	Pattern	Image	Note
TS28: testis	Present	Ubiquitous	5B , 5B'	Expression is seen in all cells.
TS28: spermatozoon	Present	Ubiquitous	5B , 5B'
TS28: interstitium of the testis	Present	Ubiquitous	5B , 5B'	Expression is stronger in the somatic cells.

5C ©

5C' ©

Specimen 5C: embryonic day 2.5 (more

)
Note: Triple labeled: red - Exosc1; green - Phalloidin; blue - DAPI.

Structure	Level	Pattern	Image	Note
TS3: 8-cell stage embryo	Present	Ubiquitous	5C , 5C'	Expression is seen in all cells, with both nuclear and cytoplasmic signal.

5D ©

5D' ©

Specimen 5D: embryonic day 3.5 (more

)
Note: Littermate control. Triple labeled: red - Exosc1; green - Phalloidin; blue - DAPI.

Structure	Level	Pattern	Image	Note
TS4: blastocyst	Present	Ubiquitous	5D' , 5D	Expression is seen in all blastocyst cells, with both nuclear and cytoplasmic signal.

5E ©

5E' ©

Specimen 5E: embryonic day 3.5; Exosc1^em1(IMPC)J/Exosc1^em1(IMPC)J (more

)
Note: Triple labeled: red - Exosc1; green - Phalloidin; blue - DAPI.

Structure	Level	Pattern	Image	Note
TS4: blastocyst	Present		5E' , 5E	Expression is lost in the nucleus; some signal remains in the cytoplasm.

5F ©

5F' ©

Specimen 5F: embryonic day 5.5 (more

)
Note: Multi-labeled: red - Exosc1; green - Cdh1 (assay MGI:7564526); white - Pou5f1 (assay MGI:7564527); blue - DAPI.

Structure	Level	Pattern	Image	Note
TS7: conceptus	Present	Ubiquitous	5F , 5F'	Expression is present in all cells and lineages.

5G ©

5G' ©

Specimen 5G: embryonic day 6.5 (more

)
Note: Multi-labeled: red - Exosc1; green - Cdh1 (assay MGI:7564526); white - Pou5f1 (assay MGI:7564527); blue - DAPI.

Structure	Level	Pattern	Image	Note
TS9: conceptus	Present	Ubiquitous	5G , 5G'	Expression is present in all cells and lineages.

5H ©

5H' ©

Specimen 5H: embryonic day 7.5 (more

)
Note: Multi-labeled: red - Exosc1; green - Cdh1 (assay MGI:7564526); white - Pou5f1 (assay MGI:7564527); blue - DAPI.

Structure	Level	Pattern	Image	Note
TS11: conceptus	Present	Ubiquitous	5H' , 5H	Expression is present in all cells and lineages.

5I ©

5I' ©

Specimen 5I: embryonic day 9.5 (more

)
Note: Multi-labeled: red - Exosc1; green - Cdh1 (assay MGI:7564526); white - Pou5f1 (assay MGI:7564527); blue - DAPI.

Structure	Level	Pattern	Image	Note
TS15: conceptus	Present	Ubiquitous	5I , 5I'	Expression is present in all cells and lineages.

6C ©

Specimen 6C: embryonic day 7.5 (more

)
Note: Littermate control.

Structure	Level	Pattern	Image	Note
TS11: conceptus	Present	Ubiquitous	6C

6D ©

Specimen 6D: embryonic day 7.5; Exosc1^em1(IMPC)J/Exosc1^em1(IMPC)J (more

)

Structure	Level	Pattern	Image	Note
TS11: conceptus	Absent		6D

6E ©

Specimen 6E: embryonic day 5.5 (more

)
Note: Littermate control. Multi-labeled: red - Exosc1; green - Cdh1 (assay MGI:7564526); yellow - Pou5f1 (assay MGI:7564527); blue - DAPI.

Structure	Level	Pattern	Image	Note
TS7: conceptus	Present		6E

6F ©

Specimen 6F: embryonic day 5.5; Exosc1^em1(IMPC)J/Exosc1^em1(IMPC)J (more

)
Note: Multi-labeled: red - Exosc1; green - Cdh1 (assay MGI:7564526); yellow - Pou5f1 (assay MGI:7564527); blue - DAPI.

Structure	Level	Pattern	Image	Note
TS7: conceptus	Absent		6F

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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