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Gene Expression Data
Assay Details
Assay
Reference: J:281311 Nakano Y, et al., Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST. Cell Rep. 2019 Apr 16;27(3):860-871.e8
Assay type: RT-PCR
MGI Accession ID: MGI:7541267
Gene symbol: Mef2d
Gene name: myocyte enhancer factor 2D
Probe: Mef2d-pC, Mef2d-pD
Assay notes: Strength assigned by curator.
Results
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Size Not Specified (b) Amount Genetic BackgroundMutant Allele(s)Sex
Inner ear E16.5 WT E16.5 TS24: macula of utricle Present Present Not Specified C57BL/6J Not Specified
Inner ear E16.5 bv/bv E16.5 TS24: macula of utricle Weak Present Not Specified involves: C57BL/6 Srrm4bv/Srrm4bvNot Specified
Neocortex E14 WT E14.0 TS22: neocortex Present Present Not Specified C57BL/6J Not Specified
Neocortex E14 bv/bv E14.0 TS22: neocortex Present Present Not Specified involves: C57BL/6 Srrm4bv/Srrm4bvNot Specified
Neocortex E16.5 WT E16.5 TS24: neocortex Present Present Not Specified C57BL/6J Not Specified
Neocortex E16.5 bv/bv E16.5 TS24: neocortex Present Present Not Specified involves: C57BL/6 Srrm4bv/Srrm4bvNot Specified
Neocortex P0 WT P0 TS27: neocortex Present Weak Not Specified C57BL/6J Not Specified
Neocortex P0 bv/bv P0 TS27: neocortex Present Weak Not Specified involves: C57BL/6 Srrm4bv/Srrm4bvNot Specified
Neocortex P16 WT P16 TS28: neocortex Present Ambiguous Not Specified C57BL/6J Not Specified
Neocortex P16 bv/bv P16 TS28: neocortex Present Ambiguous Not Specified involves: C57BL/6 Srrm4bv/Srrm4bvNot Specified
Notes:
(a) Long form. Exon 8 was spliced into the mRNA at an abnormally low rate in the inner ear of the mutant. Any splicing defect in the neocortex was mild and temporary; no splicing alterations were detected on P16.
(b) Short form.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory