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Gene Expression Data
Assay Details
Assay
Reference: J:341326 Nag P, et al., Tmem2 Deficiency Leads to Enamel Hypoplasia and Soft Enamel in Mouse. J Dent Res. 2023 Sep;102(10):1162-1171
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7539814
Gene symbol: Itgb1
Gene name: integrin beta 1 (fibronectin receptor beta)
Antibody: anti-integrin beta1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4B Control: postnatal day 14; Cemip2tm1.1Cya/? (more )
Note: Tmem2flox/flox or Tmem2flox/+ offspring without Cre were used as controls.
Structure Level Pattern Image Note
TS28: lower jaw incisor Present 4B Merged Control , 4B Integrin beta1 Control
Specimen 4B CKO: postnatal day 14; Cemip2tm1.1Cya/Cemip2tm1.1Cya, Tg(KRT14-cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: lower jaw incisor Present Regionally restricted 4B Merged CKO , 4B Integrin beta1 CKO Discontinuity of expression at intefac between stratum intermedium and basal end of secretory ameloblasts.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory