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Gene Expression Data
Assay Details
Assay
Reference: J:341326 Nag P, et al., Tmem2 Deficiency Leads to Enamel Hypoplasia and Soft Enamel in Mouse. J Dent Res. 2023 Sep;102(10):1162-1171
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7539812
Gene symbol: Amelx
Gene name: amelogenin, X-linked
Antibody: anti-amelogenin (ABT260)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3B Control: postnatal day 14; Cemip2tm1.1Cya/? (more )
Note: Tmem2flox/flox or Tmem2flox/+ offspring without Cre were used as controls.
Structure Cell Type Level Pattern Image Note
TS28: incisor enamel organ ameloblast Present Regionally restricted 3B Control Expression in secretory ameloblasts.
Specimen 3B CKO: postnatal day 14; Cemip2tm1.1Cya/Cemip2tm1.1Cya, Tg(KRT14-cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: incisor enamel organ ameloblast Weak 3B CKO Expression reduced compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory