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Gene Expression Data
Assay Details
Assay
Reference: J:165111 Doherty HE, et al., A mouse strain where basal connective tissue growth factor gene expression can be switched from low to high. PLoS One. 2010;5(9):e12909
Assay type: RT-PCR
MGI Accession ID: MGI:7539394
Gene symbol: Ccn2
Gene name: cellular communication network factor 2
Probe: Ctgf-pF, Ctgf-pR
Assay notes: Quantitative RT-PCR. Relative expression was normalized to beta-actin. The mean of Lo/+ expression was set to 85% expression.
Results
Image: 2C ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Amount Genetic BackgroundMutant Allele(s)Sex Note
Lo/+ E11.5 TS19: embryo Present Not Specified involves: 129S6/SvEvTac * C57BL/6 Ccn2tm2Mae/Ccn2+Not Specified
Hi/+ E11.5 TS19: embryo Present Not Specified involves: 129S6/SvEvTac * C57BL/6 * FVB/N Ccn2tm2Mae/Ccn2+, Tg(EIIa-cre)C5379Lmgd/?Not Specified Conditional mutant.
Notes:
(a) On average the Hi/+ embryos had a greater than ten fold increase in mRNA levels compared to the Lo/+ littermate controls, which is a nine fold increase in expression over wild type.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory