About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:165111 Doherty HE, et al., A mouse strain where basal connective tissue growth factor gene expression can be switched from low to high. PLoS One. 2010;5(9):e12909
Assay type: RT-PCR
MGI Accession ID: MGI:7539392
Gene symbol: Ccn2
Gene name: cellular communication network factor 2
Probe: Ctgf-pF, Ctgf-pR
Assay notes: Quantitative RT-PCR. Relative expression was normalized to beta-actin. The mean of Lo/+ expression was set to 85% expression.
Results
Image: 2B ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Amount Genetic BackgroundMutant Allele(s)Sex
Heart Lo/KO P m 5 TS28: heart Weak (b) Not Specified involves: 129S6/SvEvTac Ccn2tm1Mae/Ccn2tm2MaeNot Specified
Heart Lo/+ P m 5 TS28: heart Present Not Specified involves: 129S6/SvEvTac * C57BL/6 Ccn2tm2Mae/Ccn2+Not Specified
Kidney Lo/KO P m 5 TS28: metanephros Weak (c) Not Specified involves: 129S6/SvEvTac Ccn2tm1Mae/Ccn2tm2MaeNot Specified
Kidney Lo/+ P m 5 TS28: metanephros Present Not Specified involves: 129S6/SvEvTac * C57BL/6 Ccn2tm2Mae/Ccn2+Not Specified
Lung Lo/KO P m 5 TS28: lung Weak (d) Not Specified involves: 129S6/SvEvTac Ccn2tm1Mae/Ccn2tm2MaeNot Specified
Lung Lo/+ P m 5 TS28: lung Present Not Specified involves: 129S6/SvEvTac * C57BL/6 Ccn2tm2Mae/Ccn2+Not Specified
Notes:
(a) When the results from various tissues were combined, expression level in Lo/KO mice was on average 29% of wild type.
(b) Lo/KO heart tissue had significantly lower expression = 30%.
(c) Lo/KO kidney tissue had significantly lower expression = 33%.
(d) Lo/KO lung tissue had significantly lower expression = 23%.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory