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Gene Expression Data
Assay Details
Assay
Reference: J:221086 Patra D, et al., Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7537304
Gene symbol: Col2a1
Gene name: collagen, type II, alpha 1
Antibody: anti-pro-Col IIB (IIBN)
Detection system: Secondary antibody
Results
Specimen 2A: embryonic day 16.5; Mbtps1tm1Jdh/Mbtps1tm1Jdh (more )
Note: Double labeled: red - Col2a1; green - Canx (assay MGI:7537301).
Structure Level Pattern Image Note
TS24: femur Absent 2A
Specimen 2B: embryonic day 16.5; Mbtps1tm1Jdh/Mbtps1tm1Jdh, Tg(Col2a1-cre)1Bhr/0 (more )
Note: Conditional mutant. Double labeled: red - Col2a1; green - Canx (assay MGI:7537301).
Structure Cell Type Level Pattern Image Note
TS24: femur chondrocyte Present Regionally restricted 2B Significant expression detected, overlapping with Canx expression within chondrocytes.
Specimen 2E: embryonic day 16.5; Mbtps1tm1Jdh/Mbtps1tm1Jdh (more )
Note: Double labeled: green - Col2a1 protein; red - Col2a1 protein (assay MGI:7537302).
Structure Level Pattern Image Note
TS24: femur Absent 2E
Specimen 2F: embryonic day 16.5; Mbtps1tm1Jdh/Mbtps1tm1Jdh, Tg(Col2a1-cre)1Bhr/0 (more )
Note: Conditional mutant. Double labeled: green - Col2a1 protein; red - Col2a1 protein (assay MGI:7537302).
Structure Level Pattern Image Note
TS24: femur Present 2F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory