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Gene Expression Data
Assay Details
Assay
Reference: J:266925 Kim ST, et al., The N-recognin UBR4 of the N-end rule pathway is targeted to and required for the biogenesis of the early endosome. J Cell Sci. 2018 Sep 10;131(17):jcs217646
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7536907
Gene symbol: Ubr4
Gene name: ubiquitin protein ligase E3 component n-recognin 4
Antibody: anti-UBR4 (F4)
Detection system: Secondary antibody
Results
Specimen 1B +/+: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: yolk sac endoderm Present 1B +/+ inset , 1B +/+ Prominent expression in yolk sac endoderm
Specimen 1B UBR4-/-: embryonic day 9.5; Ubr4tm1.1Ytkw/Ubr4tm1.1Ytkw (more )
Structure Level Pattern Image Note
TS15: yolk sac Absent 1B UBR4-/- inset , 1B UBR4-/-
Specimen 1C UBR4: embryonic day 9.5 (more )
Note: Double labeled: red - Ubr4; green - Eea1 (assay MGI:7536908).
Structure Level Pattern Image Note
TS15: yolk sac Present Punctate 1C (merged) , 1C UBR4 , 1C UBR4 Enlarged , 1C (merged) Enlarged Expression in cytosolic puncta colocalized with Eea1-expression early endosomes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory