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Gene Expression Data
Assay Details
Assay
Reference: J:293794 Durbin MD, et al., SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects. Dev Biol. 2020 Aug 15;464(2):124-136
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7531403
Gene symbol: Scrib
Gene name: scribbled planar cell polarity
Antibody: anti-Scrib (PA5-28628)
Detection system: Secondary antibody
Results
Specimen 6E: embryonic day 11.5 (more )
Note: Double labeled: green - Scrib; red - a actinin.
Structure Level Pattern Image Note
TS19: visceral pericardium Present 6F , 6E Expression is localized at the basolateral membrane of the ventricular and atrial epicardium.
Specimen 6G: embryonic day 11.5; Shroom3Gt(ROSA53)Sor/Shroom3Gt(ROSA53)Sor (more )
Note: Double labeled: green - Scrib; red - a actinin.
Structure Level Pattern Image Note
TS19: visceral pericardium Present Regionally restricted 6G , 6H In the mutant there is no evident expression at the basolateral membrane of the ventricular epicardium (although it is still evident in the atrial basolateral membrane).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory